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dc.contributor.authorPadula, Fabrizio
dc.contributor.authorIonescu, C.
dc.contributor.authorLatronico, N.
dc.contributor.authorPaltenghi, M.
dc.contributor.authorVisioli, A.
dc.contributor.authorVivacqua, G.
dc.identifier.citationPadula, F. and Ionescu, C. and Latronico, N. and Paltenghi, M. and Visioli, A. and Vivacqua, G. 2016. Inversion-based propofol dosing for intravenous induction of hypnosis. Communications in Nonlinear Science and Numerical Simulation. 39: pp. 481-494.

© 2016 Elsevier B.V.In this paper we propose an inversion-based methodology for the computation of a feedforward action for the propofol intravenous administration during the induction of hypnosis in general anesthesia. In particular, the typical initial bolus is substituted with a command signal that is obtained by predefining a desired output and by applying an input-output inversion procedure. The robustness of the method has been tested by considering a set of patients with different model parameters, which is representative of a large population.

dc.titleInversion-based propofol dosing for intravenous induction of hypnosis
dc.typeJournal Article
dcterms.source.titleCommunications in Nonlinear Science and Numerical Simulation
curtin.departmentDepartment of Mathematics and Statistics
curtin.accessStatusFulltext not available

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