Evaluating hypoxia during air travel in healthy infants
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Up to a third of ex-preterm infants flying near term exhibit pulse oxygen saturation (SpO2) of less than 85% during air travel. A hypoxia challenge test (HCT) is recommended to evaluate the requirement for in-flight supplemental O2. The validity of the HCT in healthy, term infants has not been reported. This study aimed to characterise the in-flight hypoxia response and the accuracy of the HCT to predict this response in healthy, term infants in the first year of life. Infants (n=24: (15 male)) underwent a HCT prior to commercial air travel during which parents monitored SpO2. Thirty-two flights were undertaken with six infants completing multiple flights. The median in-flight SpO2 nadir was 87% and significantly lower than the HCT SpO2 nadir (92%: p<0.001). Infants on seven flights recorded SpO2<85% with one infant recording a HCT with a SpO2 less than 85%. There was marked variability in the in-flight SpO2 in the six infants who undertook multiple flights, and for three of these infants, the SpO2 nadir was both above and below 85%. We report that in healthy term infants an in-flight SpO2 below 85% is common and can vary considerably between flights and that the HCT poorly predicts the risk of in-flight hypoxia (SpO2<85%). As it is common for healthy term infants to have SpO2 less than 85% during air travel further research is needed to clarify whether this is an appropriate cut-off in this age group.
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Assessing the risk of in-flight hypoxia: Chronic lung disease of prematurity and children with neuromuscular disordersHall, Graham; Withers, A. (2015)Most children will experience a small, clinically insignificant drop in oxygen saturation during air travel due to the effects of altitude. Clinically significant hypoxia may occur in individuals with an underlying ...
Withers, A.; Wilson, A.; Hall, Graham (2011)In infants and children with chronic respiratory disease, hypoxia is a potential risk of aircraft travel. Although guidelines have been published to assist clinicians in assessing an individual's fitness to fly, they are ...
Gray, D.; Czövek, D.; Smith, E.; Willemse, L.; Alberts, A.; Gingl, Z.; Hall, Graham; Zar, H.; Sly, P.; Hantos, Z. (2015)Background and objective: Non-invasive techniques for measuring lung mechanics in infants are needed for a better understanding of lung growth and function, and to study the effects of prenatal factors on subsequent lung ...