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dc.contributor.authorKhanna, M.
dc.contributor.authorShackleton, C.
dc.contributor.authorVerheggen, M.
dc.contributor.authorSharp, M.
dc.contributor.authorWilson, A.
dc.contributor.authorHall, Graham
dc.identifier.citationKhanna, M. and Shackleton, C. and Verheggen, M. and Sharp, M. and Wilson, A. and Hall, G. 2013. Evaluating hypoxia during air travel in healthy infants. Thorax. 68 (12): pp. 1163-1164.

Up to a third of ex-preterm infants flying near term exhibit pulse oxygen saturation (SpO2) of less than 85% during air travel. A hypoxia challenge test (HCT) is recommended to evaluate the requirement for in-flight supplemental O2. The validity of the HCT in healthy, term infants has not been reported. This study aimed to characterise the in-flight hypoxia response and the accuracy of the HCT to predict this response in healthy, term infants in the first year of life. Infants (n=24: (15 male)) underwent a HCT prior to commercial air travel during which parents monitored SpO2. Thirty-two flights were undertaken with six infants completing multiple flights. The median in-flight SpO2 nadir was 87% and significantly lower than the HCT SpO2 nadir (92%: p<0.001). Infants on seven flights recorded SpO2<85% with one infant recording a HCT with a SpO2 less than 85%. There was marked variability in the in-flight SpO2 in the six infants who undertook multiple flights, and for three of these infants, the SpO2 nadir was both above and below 85%. We report that in healthy term infants an in-flight SpO2 below 85% is common and can vary considerably between flights and that the HCT poorly predicts the risk of in-flight hypoxia (SpO2<85%). As it is common for healthy term infants to have SpO2 less than 85% during air travel further research is needed to clarify whether this is an appropriate cut-off in this age group.

dc.publisherBMJ Group
dc.titleEvaluating hypoxia during air travel in healthy infants
dc.typeJournal Article
curtin.departmentSchool of Physiotherapy and Exercise Science
curtin.accessStatusOpen access via publisher

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