Synthesis and antiaggregant and hypotensive activity of benzo-annelated azabicyclo[m.n.0]alkanes
| dc.contributor.author | Glushkov, V. | |
| dc.contributor.author | Stryapunina, O. | |
| dc.contributor.author | Dolzhenko, Anton | |
| dc.contributor.author | Syropyatov, B. | |
| dc.contributor.author | Shklyaev, Y. | |
| dc.date.accessioned | 2017-01-30T10:46:37Z | |
| dc.date.available | 2017-01-30T10:46:37Z | |
| dc.date.created | 2011-08-18T20:01:07Z | |
| dc.date.issued | 2009 | |
| dc.identifier.citation | Glushkov, V. and Stryapunina, O. and Dolzhenko, Anton and Syropyatov, B. and Shklyaev, Y. 2009. Synthesis and antiaggregant and hypotensive activity of benzo-annelated azabicyclo[m.n.0]alkanes. Pharmaceutical Chemistry Journal. 43 (5): pp. 245-248. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/5503 | |
| dc.identifier.doi | 10.1007/s11094-009-0284-1 | |
| dc.description.abstract |
Three-component condensation of veratrole, isobutylene oxide, and aliphatic omega-chloronitriles via the Ritter reaction leads to 1-(omega-chloroalkyl)-6,7-dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolines, the reduction of which with NaBH4 yields benzoannelated azabicyclo[m.n.0]alkanes. The synthesized compounds have been tested for hypotensive and antiaggregant activity. | |
| dc.publisher | Springer | |
| dc.title | Synthesis and antiaggregant and hypotensive activity of benzo-annelated azabicyclo[m.n.0]alkanes | |
| dc.type | Journal Article | |
| dcterms.source.volume | 43 | |
| dcterms.source.number | 5 | |
| dcterms.source.startPage | 245 | |
| dcterms.source.endPage | 248 | |
| dcterms.source.issn | 0091-150X | |
| dcterms.source.title | Pharmaceutical Chemistry Journal | |
| curtin.department | School of Pharmacy | |
| curtin.accessStatus | Fulltext not available |