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dc.contributor.authorLawrence, B.
dc.contributor.authorGasson, Natalie
dc.contributor.authorBucks, R.
dc.contributor.authorTroeung, L.
dc.contributor.authorLoftus, A.
dc.date.accessioned2017-08-24T02:19:58Z
dc.date.available2017-08-24T02:19:58Z
dc.date.created2017-08-23T07:21:33Z
dc.date.issued2017
dc.identifier.citationLawrence, B. and Gasson, N. and Bucks, R. and Troeung, L. and Loftus, A. 2017. Cognitive Training and Noninvasive Brain Stimulation for Cognition in Parkinson's Disease: A Meta-analysis.. Neurorehabil Neural Repair. Online first: pp. 1-12.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/55716
dc.identifier.doi10.1177/1545968317712468
dc.description.abstract

BACKGROUND: Many people with Parkinson's disease (PD) experience cognitive decline. It is not known whether cognitive training or noninvasive brain stimulation are effective at alleviating cognitive deficits in PD. OBJECTIVE: To examine cognitive training and non-invasive brain stimulation interventions for cognition in PD. METHODS: An extensive search was conducted of published and unpublished studies in online databases. Studies were selected if they were controlled trials examining standard (not individualized) or tailored (individualized) cognitive training, repetitive transcranial magnetic stimulation (rTMS), or transcranial direct current stimulation (tDCS) in PD, with outcomes measured by standardized neuropsychological tests. RESULTS: Fourteen controlled trials met inclusion criteria. For executive function, the pooled effect size (Hedges' g) for cognitive training (standard and tailored combined) was small ( g = 0.42) but statistically significant (95% CI 0.15-0.68). The pooled effect for standard cognitive training (alone) was medium ( g = 0.51) and significant (95% CI 0.16-0.85). For attention/working memory, small pooled effect sizes were found when combining standard and tailored cognitive training ( g = 0.23; 95% CI 0.02-0.44) and for standard cognitive training alone ( g = 0.29; 95% CI 0.04-0.53), both significant. For memory, small but significant pooled effect sizes were also found when combining standard and tailored cognitive training and for standard cognitive training alone. CONCLUSIONS: The results suggest that standard and tailored cognitive training may improve executive function, attention/working memory, and memory in PD. Future studies must adopt randomized controlled trial designs to explore the therapeutic potential of these interventions.

dc.titleCognitive Training and Noninvasive Brain Stimulation for Cognition in Parkinson's Disease: A Meta-analysis.
dc.typeJournal Article
dcterms.source.volumeOnline first
dcterms.source.startPage1
dcterms.source.endPage12
dcterms.source.issn1552-6844
dcterms.source.titleNeurorehabil Neural Repair
curtin.departmentSchool of Psychology and Speech Pathology
curtin.accessStatusFulltext not available


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