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dc.contributor.authorPirillo, A.
dc.contributor.authorNorata, Giuseppe
dc.contributor.authorCatapano, A.
dc.date.accessioned2017-08-24T02:23:11Z
dc.date.available2017-08-24T02:23:11Z
dc.date.created2017-08-23T07:21:47Z
dc.date.issued2014
dc.identifier.citationPirillo, A. and Norata, G. and Catapano, A. 2014. Postprandial lipemia as a cardiometabolic risk factor. Current Medical Research and Opinion. 30 (8): pp. 1489-1503.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/56246
dc.identifier.doi10.1185/03007995.2014.909394
dc.description.abstract

High levels of fasting circulating triglycerides (TG) represent an independent risk factor for cardiovascular disease. In western countries, however, people spend most time in postprandial conditions, with continuous fluctuation of lipemia due to increased levels of TG-rich lipoproteins (TRLs), including chylomicrons (CM), very low density lipoproteins (VLDL), and their remnants. Several factors contribute to postprandial lipid metabolism, including dietary, physiological, pathological and genetic factors. The presence of coronary heart disease, type 2 diabetes, insulin resistance and obesity is associated with higher postprandial TG levels compared with healthy conditions; this association is present also in subjects with normal fasting TG levels. Increasing evidence indicates that impaired metabolism of postprandial lipoproteins contributes to the pathogenesis of coronary artery disease, suggesting that lifestyle modifications as well as pharmacological approaches aimed at reducing postprandial TG levels might help to decrease the cardiovascular risk. © 2014 Informa UK Ltd.

dc.publisherLibrapharm
dc.titlePostprandial lipemia as a cardiometabolic risk factor
dc.typeJournal Article
dcterms.source.volume30
dcterms.source.number8
dcterms.source.startPage1489
dcterms.source.endPage1503
dcterms.source.issn0300-7995
dcterms.source.titleCurrent Medical Research and Opinion
curtin.departmentSchool of Biomedical Sciences
curtin.accessStatusFulltext not available


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