Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Pro-nociceptive and anti-nociceptive effects of a conditioned pain modulation protocol in participants with chronic low back pain and healthy control subjects

    Access Status
    Fulltext not available
    Authors
    Rabey, M.
    Poon, C.
    Wray, J.
    Thamajaree, C.
    East, R.
    Slater, Helen
    Date
    2014
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Rabey, M. and Poon, C. and Wray, J. and Thamajaree, C. and East, R. and Slater, H. 2014. Pro-nociceptive and anti-nociceptive effects of a conditioned pain modulation protocol in participants with chronic low back pain and healthy control subjects. Manual Therapy.
    Source Title
    Manual Therapy
    DOI
    10.1016/j.math.2015.02.011
    ISSN
    1356-689X
    School
    School of Physiotherapy and Exercise Science
    URI
    http://hdl.handle.net/20.500.11937/5652
    Collection
    • Curtin Research Publications
    Abstract

    Background: People with chronic pain may exhibit pro-nociceptive phenotypes characterised partly by reduced conditioned pain modulation (CPM). Characterising variability in CPM in people with chronic low back pain (CLBP) may inform management. Objectives: To investigate pro/anti-nociceptive effects of a CPM protocol in age/sex-matched healthy controls (HCs) and people with CLBP. Design: Case-controlled trial (64 participants/group). Method: The CPM protocol involved: test stimulus (TS) (noxious pressure applied by algometer to lumbar region); conditioning stimulus (CS) (noxious heat applied by thermode to dorsal hand). CPM recruitment was measured by the change in pain intensity (rated on a numeric rating scale (NRS)) of the TS in the presence and absence of the CS. Results: Responses to this CPM protocol were variable for both groups with measures consistent with either inhibitory or facilitatory effects. A significantly greater proportion of facilitatory responses were seen in the CLBP cohort compared to HCs (73% versus 31%). In response to the CS, participants with CLBP demonstrated a mean increase in NRS scores (mean 1.3 points; p<0.001), while HCs did not (mean-0.2 points; p=0.35) and the between-group difference in change scores was significant (mean 1.4 points; p<0.001; effect size (Hedges' g): 1.03). Conclusion: In HCs and participants with CLBP this CPM protocol elicited responses consistent with varying pro/anti-nociceptive effects. The higher proportion of participants with CLBP demonstrating a facilitatory response suggests a pro-nociceptive phenotype may characterise this cohort.

    Related items

    Showing items related by title, author, creator and subject.

    • Pain provocation following sagittal plane repeated movements in people with chronic low back pain: Associations with pain sensitivity and psychological profiles
      Rabey, Martin; Smith, Anne; Beales, Darren; Slater, Helen; O'Sullivan, Peter (2017)
      Background and aims Provocative pain responses following standardised protocols of repeated sagittal plane spinal bending have not been reported in people with chronic low back pain (CLBP). Potential differing pain responses ...
    • Individuals with chronic low back pain have greater difficulty in engaging in positive lifestyle behaviours than those without back pain: An assessment of health literacy
      Briggs, Andrew; Jordan, J.; O'Sullivan, Peter; Buchbinder, R.; Burnett, A.; Osborne, R.; Straker, Leon (2011)
      Background: Despite the large volume of research dedicated to understanding chronic low back pain (CLBP), patient outcomes remain modest while healthcare costs continue to rise, creating a major public health burden. ...
    • Consumers’ experiences of back pain in rural Western Australia: Access to information and services, and self-management behaviours.
      Briggs, Andrew; Slater, Helen; Bunzli, S.; Jordan, J.; Davies, S.; Smith, Anne; Quintner, J. (2012)
      Background: Coordinated, interdisciplinary services, supported by self-management underpin effective management for chronic low back pain (CLBP). However, a combination of system, provider and consumer-based barriers exist ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.