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    A comprehensive evaluation of a two-channel portable monitor to "rule in" obstructive sleep apnea

    Access Status
    Fulltext not available
    Authors
    Ward, Kim
    McArdle, N.
    James, A.
    Bremner, A.
    Simpson, L.
    Cooper, M.
    Palmer, L.
    Fedson, A.
    Mukherjee, S.
    Hillman, D.
    Date
    2015
    Type
    Journal Article
    
    Metadata
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    Citation
    Ward, K. and McArdle, N. and James, A. and Bremner, A. and Simpson, L. and Cooper, M. and Palmer, L. et al. 2015. A comprehensive evaluation of a two-channel portable monitor to "rule in" obstructive sleep apnea. Journal of Clinical Sleep Medicine. 11 (4): pp. 433-444.
    Source Title
    Journal of Clinical Sleep Medicine
    DOI
    10.5664/jcsm.4600
    ISSN
    1550-9389
    School
    Curtin-Monash Accident Research Centre
    URI
    http://hdl.handle.net/20.500.11937/66875
    Collection
    • Curtin Research Publications
    Abstract

    © 2015, American Academy of Sleep Medicine. All rights reserved. Study Objectives: We hypothesized that a dual-channel portable monitor (PM) device could accurately identify patients who have a high pretest probability of obstructive sleep apnea (OSA), and we evaluated factors that may contribute to variability between PM and polysomnography (PSG) results. Methods: Consecutive clinic patients (N = 104) with possible OSA completed a home PM study, a PM study simultaneous with laboratory PSG, and a second home PM study. Uniform data analysis methods were applied to both PM and PSG data. Primary outcomes of interest were the positive likelihood ratio (LR+) and sensitivity of the PM device to "rule-in" OSA, defined as an apnea-hypopnea index (AHI) = 5 events/h on PSG. Effects of different test environment and study nights, and order of study and analysis methods (manual compared to automated) on PM diagnostic accuracy were assessed. Results: The PM has adequate LR+ (4.8), sensitivity (80%), and specificity (83%) for detecting OSA in the unattended home setting when benchmarked against laboratory PSG, with better LR+ ( > 5) and specificity (100%) and unchanged sensitivity (80%) in the simultaneous laboratory comparison. There were no significant night-night (all p > 0.10) or study order effects (home or laboratory first, p = 0.08) on AHI measures. Manual PM data review improved case finding accuracy, although this was not statistically significant (all p > 0.07). Misclassification was more frequent where OSA was mild. Conclusions: Overall performance of the PM device is consistent with current recommended criteria for an "acceptable" device to confidently "rule-in" OSA (AHI = 5 events/h) in a high pretest probability clinic population. Our data support the utility of simple two-channel diagnostic devices to confirm the diagnosis of OSA in the home environment.

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