A comprehensive evaluation of a two-channel portable monitor to "rule in" obstructive sleep apnea
dc.contributor.author | Ward, Kim | |
dc.contributor.author | McArdle, N. | |
dc.contributor.author | James, A. | |
dc.contributor.author | Bremner, A. | |
dc.contributor.author | Simpson, L. | |
dc.contributor.author | Cooper, M. | |
dc.contributor.author | Palmer, L. | |
dc.contributor.author | Fedson, A. | |
dc.contributor.author | Mukherjee, S. | |
dc.contributor.author | Hillman, D. | |
dc.date.accessioned | 2018-05-18T07:56:24Z | |
dc.date.available | 2018-05-18T07:56:24Z | |
dc.date.created | 2018-05-18T00:23:21Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Ward, K. and McArdle, N. and James, A. and Bremner, A. and Simpson, L. and Cooper, M. and Palmer, L. et al. 2015. A comprehensive evaluation of a two-channel portable monitor to "rule in" obstructive sleep apnea. Journal of Clinical Sleep Medicine. 11 (4): pp. 433-444. | |
dc.identifier.uri | http://hdl.handle.net/20.500.11937/66875 | |
dc.identifier.doi | 10.5664/jcsm.4600 | |
dc.description.abstract |
© 2015, American Academy of Sleep Medicine. All rights reserved. Study Objectives: We hypothesized that a dual-channel portable monitor (PM) device could accurately identify patients who have a high pretest probability of obstructive sleep apnea (OSA), and we evaluated factors that may contribute to variability between PM and polysomnography (PSG) results. Methods: Consecutive clinic patients (N = 104) with possible OSA completed a home PM study, a PM study simultaneous with laboratory PSG, and a second home PM study. Uniform data analysis methods were applied to both PM and PSG data. Primary outcomes of interest were the positive likelihood ratio (LR+) and sensitivity of the PM device to "rule-in" OSA, defined as an apnea-hypopnea index (AHI) = 5 events/h on PSG. Effects of different test environment and study nights, and order of study and analysis methods (manual compared to automated) on PM diagnostic accuracy were assessed. Results: The PM has adequate LR+ (4.8), sensitivity (80%), and specificity (83%) for detecting OSA in the unattended home setting when benchmarked against laboratory PSG, with better LR+ ( > 5) and specificity (100%) and unchanged sensitivity (80%) in the simultaneous laboratory comparison. There were no significant night-night (all p > 0.10) or study order effects (home or laboratory first, p = 0.08) on AHI measures. Manual PM data review improved case finding accuracy, although this was not statistically significant (all p > 0.07). Misclassification was more frequent where OSA was mild. Conclusions: Overall performance of the PM device is consistent with current recommended criteria for an "acceptable" device to confidently "rule-in" OSA (AHI = 5 events/h) in a high pretest probability clinic population. Our data support the utility of simple two-channel diagnostic devices to confirm the diagnosis of OSA in the home environment. | |
dc.title | A comprehensive evaluation of a two-channel portable monitor to "rule in" obstructive sleep apnea | |
dc.type | Journal Article | |
dcterms.source.volume | 11 | |
dcterms.source.number | 4 | |
dcterms.source.startPage | 433 | |
dcterms.source.endPage | 444 | |
dcterms.source.issn | 1550-9389 | |
dcterms.source.title | Journal of Clinical Sleep Medicine | |
curtin.department | Curtin-Monash Accident Research Centre | |
curtin.accessStatus | Fulltext not available |
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