Show simple item record

dc.contributor.authorSørensen, J.
dc.contributor.authorBenfield, A.
dc.contributor.authorWollenberg, R.
dc.contributor.authorWestphal, K.
dc.contributor.authorWimmer, R.
dc.contributor.authorNielsen, M.
dc.contributor.authorNielsen, K.
dc.contributor.authorCarere, J.
dc.contributor.authorCovarelli, Lorenzo
dc.contributor.authorBeccari, G.
dc.contributor.authorPowell, J.
dc.contributor.authorYamashino, T.
dc.contributor.authorKogler, H.
dc.contributor.authorSondergaard, T.
dc.contributor.authorGardiner, D.
dc.identifier.citationSørensen, J. and Benfield, A. and Wollenberg, R. and Westphal, K. and Wimmer, R. and Nielsen, M. and Nielsen, K. et al. 2018. The cereal pathogen Fusarium pseudograminearum produces a new class of active cytokinins during infection. Molecular Plant Pathology. 19 (5): pp. 1140-1154.

The fungal pathogen Fusarium pseudograminearum causes important diseases of wheat and barley. During a survey of secondary metabolites produced by this fungus, a novel class of cytokinins, herein termed Fusarium cytokinins, was discovered. Cytokinins are known for their growth-promoting and anti-senescence activities, and the production of a cytokinin mimic by what was once considered as a necrotrophic pathogen that promotes cell death and senescence challenges the simple view that this pathogen invades its hosts by employing a barrage of lytic enzymes and toxins. Through genome mining, a gene cluster in the F. pseudograminearum genome for the production of Fusarium cytokinins was identified and the biosynthetic pathway was established using gene knockouts. The Fusarium cytokinins could activate plant cytokinin signalling, demonstrating their genuine hormone mimicry. In planta analysis of the transcriptional response to one Fusarium cytokinin suggests extensive reprogramming of the host environment by these molecules, possibly through crosstalk with defence hormone signalling pathways.

dc.publisherWiley-Blackwell Publishing Ltd.
dc.titleThe cereal pathogen Fusarium pseudograminearum produces a new class of active cytokinins during infection
dc.typeJournal Article
dcterms.source.titleMolecular Plant Pathology
curtin.departmentCentre for Crop and Disease Management (CCDM)
curtin.accessStatusFulltext not available

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record