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    Glutamine and the immune system

    Access Status
    Fulltext not available
    Authors
    Cruzat, Vinicius
    Newsholme, P.
    Date
    2017
    Type
    Book Chapter
    
    Metadata
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    Citation
    Cruzat, V. and Newsholme, P. 2017. Glutamine and the immune system. In Nutrition, Immunity, and Infection, 357-374.
    Source Title
    Nutrition, Immunity, and Infection
    DOI
    10.1201/9781315118901
    ISBN
    9781482253986
    School
    School of Pharmacy and Biomedical Sciences
    URI
    http://hdl.handle.net/20.500.11937/71576
    Collection
    • Curtin Research Publications
    Abstract

    © 2018 by Taylor & Francis Group, LLC. Glutamine is recognized as a crucial and versatile amino acid for cell survival and growth, playing an important role in metabolism. Moreover, compared to all other amino acids in the body, glutamine is present at the highest extracellular concentration, and is considered the most abundant free amino acid. In fact, in addition to glucose, glutamine represents a primary nutrient for maintenance of the body’s homeostasis (Newsholme et al. 2003a).

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    • Effects of supplementation with free glutamine and the dipeptide alanyl-glutamine on parameters of muscle damage and inflammation in rats submitted to prolonged exercise
      Cruzat, Vinicius; Rogero, M.; Tirapegui, J. (2010)
      In this study, we investigated the effect of the supplementation with the dipeptide L-alanyl-L-glutamine (DIP) and a solution containing L-glutamine and L-alanine on plasma levels markers of muscle damage and levels of ...
    • L-glutamine and L-alanine supplementation increase glutamine-glutathione axis and muscle HSP-27 in rats trained using a progressive high-intensity resistance exercise
      Leite, J.; Raizel, R.; Hypólito, T.; Dos Santos Rosa, T.; Cruzat, Vinicius; Tirapegui, J. (2016)
      In this study we investigated the chronic effects of oral L-glutamine and L-alanine supplementation, either in their free or dipeptide form, on glutamine-glutathione (GLN-GSH) axis and cytoprotection mediated by HSP-27 ...
    • Glutamine: Metabolism and immune function, supplementation and clinical translation
      Cruzat, Vinicius; Rogero, M.; Keane, Kevin; Curi, R.; Newsholme, Philip (2018)
      © 2018 by the authors. Licensee MDPI, Basel, Switzerland. Glutamine is the most abundant and versatile amino acid in the body. In health and disease, the rate of glutamine consumption by immune cells is similar or greater ...
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