Glutamine and the immune system
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Authors
Cruzat, Vinicius
Newsholme, P.
Date
2017Type
Book Chapter
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Cruzat, V. and Newsholme, P. 2017. Glutamine and the immune system. In Nutrition, Immunity, and Infection, 357-374.
Source Title
Nutrition, Immunity, and Infection
ISBN
School
School of Pharmacy and Biomedical Sciences
Collection
Abstract
© 2018 by Taylor & Francis Group, LLC. Glutamine is recognized as a crucial and versatile amino acid for cell survival and growth, playing an important role in metabolism. Moreover, compared to all other amino acids in the body, glutamine is present at the highest extracellular concentration, and is considered the most abundant free amino acid. In fact, in addition to glucose, glutamine represents a primary nutrient for maintenance of the body’s homeostasis (Newsholme et al. 2003a).
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Cruzat, Vinicius; Rogero, M.; Tirapegui, J. (2010)In this study, we investigated the effect of the supplementation with the dipeptide L-alanyl-L-glutamine (DIP) and a solution containing L-glutamine and L-alanine on plasma levels markers of muscle damage and levels of ...
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Leite, J.; Raizel, R.; Hypólito, T.; Dos Santos Rosa, T.; Cruzat, Vinicius; Tirapegui, J. (2016)In this study we investigated the chronic effects of oral L-glutamine and L-alanine supplementation, either in their free or dipeptide form, on glutamine-glutathione (GLN-GSH) axis and cytoprotection mediated by HSP-27 ...
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Cruzat, Vinicius; Rogero, M.; Keane, Kevin; Curi, R.; Newsholme, Philip (2018)© 2018 by the authors. Licensee MDPI, Basel, Switzerland. Glutamine is the most abundant and versatile amino acid in the body. In health and disease, the rate of glutamine consumption by immune cells is similar or greater ...