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    Gastrointestinal microbiota and metabolite biomarkers in children with autism spectrum disorders

    Access Status
    Fulltext not available
    Authors
    Wang, L.
    Conlon, M.
    Christophersen, Claus
    Sorich, M.
    Angley, M.
    Date
    2014
    Type
    Journal Article
    
    Metadata
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    Citation
    Wang, L. and Conlon, M. and Christophersen, C. and Sorich, M. and Angley, M. 2014. Gastrointestinal microbiota and metabolite biomarkers in children with autism spectrum disorders. BIOMARKERS IN MEDICINE. 8 (3): pp. 331-344.
    Source Title
    BIOMARKERS IN MEDICINE
    DOI
    10.2217/bmm.14.12
    ISSN
    1752-0363
    School
    School of Molecular and Life Sciences (MLS)
    URI
    http://hdl.handle.net/20.500.11937/72558
    Collection
    • Curtin Research Publications
    Abstract

    Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Many affected individuals also display symptoms of gastrointestinal (GI) disturbance, suggesting GI factors may play an important role in the pathogenesis of ASD and/or related complications. The current review will focus on evidence supporting a role for the GI microbiota and their fermentation products in the etiology and/or symptoms of ASD, and their potential use as biomarkers. GI-related biomarkers could potentially enable early identification of ASD at risk of GI disturbance, and thereby guide targeted interventions, potentially improving the health and quality of life of affected individuals. © 2014 Future Medicine Ltd.

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