Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Structure-informed detection and quantification of peptides in food and biological fluids

    Access Status
    Fulltext not available
    Authors
    Agyei, D.
    Pan, S.
    Acquah, C.
    Bekhit, A.
    Danquah, Michael
    Date
    2017
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Agyei, D. and Pan, S. and Acquah, C. and Bekhit, A. and Danquah, M. 2017. Structure-informed detection and quantification of peptides in food and biological fluids. Journal of Food Biochemistry.
    Source Title
    Journal of Food Biochemistry
    DOI
    10.1111/jfbc.12482
    ISSN
    0145-8884
    School
    Curtin Malaysia
    URI
    http://hdl.handle.net/20.500.11937/73238
    Collection
    • Curtin Research Publications
    Abstract

    © 2017 Wiley Periodicals, Inc. Peptides with biological properties, that is, bioactive peptides, are a class of biomolecules whose health-promoting properties are increasingly being exploited in food and health products. However, research on targeted techniques for the detection and quantification of these peptides is still in its infancy. Such information is needed in order to enhance the biological and chemometric characterization of peptides and their subsequent application in the functional food and pharmaceutical industries. In this review, the role of classic techniques such as electrophoretic, chromatographic, and peptide mass spectrometry in the structure-informed detection and quantitation of bioactive peptides are discussed. Prospects for the use of aptamers in the characterization of bioactive peptides are also discussed. Practical applications: Although bioactive peptides have huge potential applications in the functional foods and health area, there are limited techniques in enhancing throughput detection, quantification, and characterization of these peptides. This review discusses state-of-the-art techniques relevant in complementing bioactive detection and profiling irrespective of the small number of amino acid units. Insights into challenges, possible remedies and prevailing areas requiring thorough research in the extant literature for food chemists and biotechnologists are also presented.

    Related items

    Showing items related by title, author, creator and subject.

    • Prospects in the use of aptamers for characterizing the structure and stability of bioactive proteins and peptides in food
      Agyei, D.; Acquah, C.; Tan, K.; Hii, H.; Rajendran, S.; Udenigwe, C.; Danquah, Michael (2018)
      Food-derived bioactive proteins and peptides have gained acceptance among researchers, food manufacturers and consumers as health-enhancing functional food components that also serve as natural alternatives for disease ...
    • Bioprocess challenges to the isolation and purification of bioactive peptides
      Agyei, D.; Ongkudon, C.; Wei, C.; Chan, A.; Danquah, Michael (2016)
      Published by Elsevier B.V. All rights reserved. Food protein-derived bioactive peptides (BPs) have been reported to trigger certain physiological responses in the body, thereby influencing health positively. These peptides ...
    • Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides
      Agyei, D.; Danquah, Michael (2011)
      Recent studies have shown that most peptide sequences encrypted in food proteins confer bioactive properties after release by enzymatic hydrolysis. Such bioactivities, which include antithrombotic, antihypertensive, ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.