A new measure of decompression sickness in the rat
MetadataShow full item record
In this study we assessed the reliability of a tilting-board grip score as a measure of decompression sickness in rats. In experiments using a hyperbaric compression/decompression protocol, rats were observed for signs of decompression sickness and their grip strength measured on a tilting particle board hinged to a metal frame. Angles at which rats lost grip were converted to gravitational vectors. Decreased mean grip scores following decompression were fitted to a logistic regression model with strain, age, and weight. Decrease in grip score was significantly associated with observed decompression sickness (P=0.0036). The log odds ratio for decompression sickness = 1.40 (decrease in grip score). In rats with no decrease in mean grip score there was a 50% probability of decompression sickness (pDCS). This increased steadily with decreases in mean grip score. A decrease of 0.3 had a 60% pDCS, a decrease of 0.6 had a 70% pDCS, and a decrease of 2.1 had a 95% pDCS. The tilting board grip score is a reliable measure of the probability of decompression sickness. © 2014 Peter Buzzacott et al.
Showing items related by title, author, creator and subject.
Mazur, A.; Lambrechts, K.; Buzzacott, Peter; Wang, Q.; Belhomme, M.; Theron, M.; Mansourati, J.; Guerrero, F. (2014)Several studies have demonstrated that endothelial function is impaired following a dive even without decompression sickness. During this study we determined the effect of decompression sickness on endothelium-dependent ...
Zhang, K.; Wang, D.; Jiang, Z.; Ning, X.; Buzzacott, Peter; Xu, W. (2016)© 2016 The Author(s). Previous studies have documented that decompression led to endothelial dysfunction with controversial results. This study aimed to clarify the relationship between endothelial dysfunction, bubble ...
Meuleners, Lynn (2001)Assessments of quality of life (QOL) for adolescents have received relatively little attention in the literature. Although there is no consensus on the definition of adolescent QOL and what aspects should be measured, it ...