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dc.contributor.authorBuzzacott, Peter
dc.contributor.authorMazur, A.
dc.contributor.authorWang, Q.
dc.contributor.authorLambrechts, K.
dc.contributor.authorTheron, M.
dc.contributor.authorMansourati, J.
dc.contributor.authorGuerrero, F.
dc.identifier.citationBuzzacott, P. and Mazur, A. and Wang, Q. and Lambrechts, K. and Theron, M. and Mansourati, J. and Guerrero, F. 2014. A new measure of decompression sickness in the rat. BioMed Research International. 2014.

In this study we assessed the reliability of a tilting-board grip score as a measure of decompression sickness in rats. In experiments using a hyperbaric compression/decompression protocol, rats were observed for signs of decompression sickness and their grip strength measured on a tilting particle board hinged to a metal frame. Angles at which rats lost grip were converted to gravitational vectors. Decreased mean grip scores following decompression were fitted to a logistic regression model with strain, age, and weight. Decrease in grip score was significantly associated with observed decompression sickness (P=0.0036). The log odds ratio for decompression sickness = 1.40 (decrease in grip score). In rats with no decrease in mean grip score there was a 50% probability of decompression sickness (pDCS). This increased steadily with decreases in mean grip score. A decrease of 0.3 had a 60% pDCS, a decrease of 0.6 had a 70% pDCS, and a decrease of 2.1 had a 95% pDCS. The tilting board grip score is a reliable measure of the probability of decompression sickness. © 2014 Peter Buzzacott et al.

dc.publisherHindawi Publishing Corporation
dc.titleA new measure of decompression sickness in the rat
dc.typeJournal Article
dcterms.source.titleBioMed Research International
curtin.departmentSchool of Nursing, Midwifery and Paramedicine
curtin.accessStatusFulltext not available

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