Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs
dc.contributor.author | Jhanker, Yeakuty Marzan | |
dc.contributor.supervisor | Heather Benson | en_US |
dc.date.accessioned | 2019-03-26T05:04:20Z | |
dc.date.available | 2019-03-26T05:04:20Z | |
dc.date.issued | 2018 | en_US |
dc.identifier.uri | http://hdl.handle.net/20.500.11937/74955 | |
dc.description.abstract |
This research focused on transdermal penetration enhancement of peptides, peptide-like and lipophilic drugs by employing physical and chemical penetration enhancers. Three potential physical penetration enhancement tools, namely elongated microparticles, microneedles and Dermaroller®, significantly increased in vitro skin penetration and retention with further enhancement achieved by formulating with a chemical enhancer. We concluded that physical and chemical penetration enhancers are suitable tools for transdermal drug delivery. | en_US |
dc.publisher | Curtin University | en_US |
dc.title | Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs | en_US |
dc.type | Thesis | en_US |
dcterms.educationLevel | PhD | en_US |
curtin.department | Pharmacy and Biomedical Sciences | en_US |
curtin.accessStatus | Open access | en_US |
curtin.faculty | Health Sciences | en_US |