Traffic emissions are associated with reduced fetal growth in areas of Perth, Western Australia: An application of the AusRoads dispersion model
|dc.identifier.citation||Pereira, G. and Nassar, N. and Cook, A. and Bower, C. 2011. Traffic emissions are associated with reduced fetal growth in areas of Perth, Western Australia: An application of the AusRoads dispersion model. Australian and New Zealand Journal of Public Health. 35 (5): pp. 451-458.|
Background: This study, in a region with relatively low industrial activity, used a highly specific marker for traffic emissions, accounted for the inherent fetal growth potential, and used complete record linkage of births, midwife notifications, deaths, hospital morbidity and birth defect records. Methods: Clinical records were obtained for pregnancies between 2000 and 2006 in three areas of Perth, Western Australia (n=3,501). We used carbon monoxide as a marker for locally derived traffic emissions, and assessed exposure using the AusRoads dispersion model. Fetal growth was characterised by proportion of optimal birth weight and investigated using multivariate mixed-effects regression. Results: Exposure in the third trimester was associated with a -0.49% (sd=0.23%) change in proportion of optimal birth weight per 10 µg/m3 increase in locally derived traffic emissions. However, this result was confined to one of the three study areas due to elevated exposure misclassification among women in the other two areas. Among this group, a neonate who would have otherwise attained an optimal birth weight of 3.5 kg would be expected to be born 58 g lighter for an interquartile increase in third trimester exposure, which was approximately half of the effect observed for maternal smoking during pregnancy. Conclusion: We observed an association between maternal exposure to traffic emissions and reduced fetal growth. This effect was supported by sensitivity analyses but only observed in one of the three study areas. Further studies are required to corroborate our results.
|dc.title||Traffic emissions are associated with reduced fetal growth in areas of Perth, Western Australia: An application of the AusRoads dispersion model|
|dcterms.source.title||Australian and New Zealand Journal of Public Health|
|curtin.accessStatus||Fulltext not available|
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