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dc.contributor.authorGebremedhin, Amanuel Tesfay
dc.contributor.authorRegan, Annette
dc.contributor.authorBall, Stephen
dc.contributor.authorBetrán, A.P.
dc.contributor.authorFoo, D.
dc.contributor.authorGissler, M.
dc.contributor.authorHåberg, S.E.
dc.contributor.authorMalacova, Eva
dc.contributor.authorMarinovich, M. Luke
dc.contributor.authorPereira, Gavin
dc.identifier.citationGebremedhin, A.T. and Regan, A.K. and Ball, S. and Betrán, A.P. and Foo, D. and Gissler, M. and Håberg, S.E. et al. 2019. Effect of interpregnancy interval on gestational diabetes: a retrospective matched cohort study. Annals of Epidemiology. 39: pp. 33-38.e3.

© 2019 The Authors Purpose: To examine the association between interpregnancy interval (IPI) and gestational diabetes using both within-mother and between-mother comparisons. Methods: A retrospective cohort study of 103,909 women who delivered three or more consecutive singleton births (n = 358,046) between 1 January 1980 and 31 December 2015 in Western Australia. The association between IPI and gestational diabetes was estimated using conditional logistic regression, matching pregnancies to the same mother and adjusted for factors that vary within-mother across pregnancies. For comparison with previous studies, we also applied unmatched logistic regression (between-mother analysis). Results: The conventional between-mother analysis resulted in adjusted odds ratios (aOR) of 1.13 (95% CI, 1.06–1.21) for intervals of 24–59 months and 1.51 (95% CI, 1.33–1.70) for intervals of 120 or more months, compared with IPI of 18–23 months. In addition, short IPIs were associated with lower odds of gestational diabetes with (aOR: 0.89; 95% CI, 0.82–0.97) for 6–11 months and (aOR: 0.92; 95% CI, 0.85–0.99) for 12–17-month. In comparison, the adjusted within-mother matched analyses showed no statistically significant association between IPIs and gestational diabetes. All effect estimates were attenuated using the within-mother matched model. Conclusion: Our findings do not support the hypothesis that short IPI (<6 months) increases the risk of gestational diabetes and suggest that observed associations in previous research might be attributable to confounders that vary between mothers.

dc.subjectBirth intervals
dc.subjectBirth spacing
dc.subjectGestational diabetes
dc.subjectInterpregnancy intervals
dc.subjectMatched analysis
dc.subjectPregnancy complications
dc.titleEffect of interpregnancy interval on gestational diabetes: a retrospective matched cohort study
dc.typeJournal Article
dcterms.source.titleAnnals of Epidemiology
curtin.departmentSchool of Public Health
curtin.departmentSchool of Nursing, Midwifery and Paramedicine
curtin.accessStatusOpen access
curtin.facultyFaculty of Health Sciences
curtin.contributor.orcidPereira, Gavin [0000-0003-3740-8117]
curtin.contributor.researcheridPereira, Gavin [D-7136-2014]
curtin.contributor.scopusauthoridMalacova, Eva [16242025400]
curtin.contributor.scopusauthoridGebremedhin, Amanuel Tesfay [56412162800]
curtin.contributor.scopusauthoridRegan, Annette [25932252200]
curtin.contributor.scopusauthoridPereira, Gavin [35091486200]
curtin.contributor.scopusauthoridBall, Stephen [55676853700]

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