Identification and characterisation of fosfomycin resistance in Escherichia coli urinary tract infection isolates from Australia
MetadataShow full item record
© 2020 Elsevier Ltd
Of 1033 Escherichia coli urinary tract infection isolates collected from females >12 years of age in Australia in 2019, only 2 isolates were resistant to fosfomycin with a minimum inhibitory concentration (MIC) of >256 mg/L. Despite having different multilocus sequence types, the two isolates harboured an identical plasmid-encoded fosA4 gene. The fosA4 gene has previously been identified in a single clinical E. coli isolate cultured in Japan in 2014. Each fosfomycin-resistant isolate harboured two conjugative plasmids that possessed an array of genes conferring resistance to aminoglycosides, β-lactams, macrolides, quinolones, sulfonamides and/or trimethoprim.
Showing items related by title, author, creator and subject.
Udo, Edet Ekpenyong (1991)Fifty three Staphylococcus aureus isolates were obtained from three centres, two hospitals and a private pathology laboratory, and studied for susceptibility to bacteriophages, resistance to antimicrobial agents and plasmid ...
Increasing incidence of Escherichia coli bacteraemia is driven by an increase in antibiotic-resistant isolates: Electronic database study in Oxfordshire 1999-2011Schlackow, I.; Stoesser, N.; Walker, A.; Crook, D.; Peto, T.; Wyllie, D.; Bejon, P.; Berendt, T.; Bunch, C.; Finney, J.; Gearing, J.; Jones, H.; O'Connor, L.; Robinson, James; Shine, B.; Waller, D. (2012)Objectives: To investigate trends in Escherichia coli resistance, bacteraemia rates and post-bacteraemia outcomes over time. Methods: Trends in E. coli bacteraemia incidence were monitored from January 1999 to June 2011 ...
Epidemiology and antimicrobial susceptibility profiles of pathogens causing urinary tract infections in the Asia-Pacific region: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2010-2013Jean, S.; Coombs, Geoffrey; Ling, T.; Balaji, V.; Rodrigues, C.; Mikamo, H.; Kim, M.; Rajasekaram, D.; Mendoza, M.; Tan, T.; Kiratisin, P.; Ni, Y.; Weinman, B.; Xu, Y.; Hsueh, P. (2016)A total of 9599 isolates of Gram-negative bacteria (GNB) causing urinary tract infections (UTIs) were collected from 60 centres in 13 countries in the Asia-Pacific region from 2010-2013. These isolates comprised ...