View Item 

Show simple item record

Identification and characterisation of fosfomycin resistance in Escherichia coli urinary tract infection isolates from Australia

dc.contributor.authorMowlaboccus, S.
dc.contributor.authorDaley, D.
dc.contributor.authorPang, S.
dc.contributor.authorGottlieb, T.
dc.contributor.authorMerlino, J.
dc.contributor.authorNimmo, G.R.
dc.contributor.authorGeorge, N.
dc.contributor.authorKorman, T.M.
dc.contributor.authorStreitberg, R.
dc.contributor.authorRobson, J.
dc.contributor.authorPeachey, G.
dc.contributor.authorCollignon, P.
dc.contributor.authorBradbury, S.
dc.contributor.authorColombi, Elena
dc.contributor.authorRamsay, Josh
dc.contributor.authorRogers, B.A.
dc.contributor.authorCoombs, G.W.
dc.date.accessioned2020-10-06T05:35:05Z
dc.date.available2020-10-06T05:35:05Z
dc.date.issued2020
dc.identifier.citationMowlaboccus, S. and Daley, D. and Pang, S. and Gottlieb, T. and Merlino, J. and Nimmo, G.R. and George, N. et al. 2020. Identification and characterisation of fosfomycin resistance in Escherichia coli urinary tract infection isolates from Australia. International Journal of Antimicrobial Agents. 56 (4): Article No. 106121.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/81354
dc.identifier.doi10.1016/j.ijantimicag.2020.106121
dc.description.abstract

© 2020 Elsevier Ltd

Of 1033 Escherichia coli urinary tract infection isolates collected from females >12 years of age in Australia in 2019, only 2 isolates were resistant to fosfomycin with a minimum inhibitory concentration (MIC) of >256 mg/L. Despite having different multilocus sequence types, the two isolates harboured an identical plasmid-encoded fosA4 gene. The fosA4 gene has previously been identified in a single clinical E. coli isolate cultured in Japan in 2014. Each fosfomycin-resistant isolate harboured two conjugative plasmids that possessed an array of genes conferring resistance to aminoglycosides, β-lactams, macrolides, quinolones, sulfonamides and/or trimethoprim.
dc.languageeng
dc.publisherElsevier
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectEscherichia coli
dc.subjectFosfomycin resistance
dc.subjectUrinary tract infection
dc.subjectfosA4
dc.titleIdentification and characterisation of fosfomycin resistance in Escherichia coli urinary tract infection isolates from Australia
dc.typeJournal Article
dcterms.source.volume56
dcterms.source.number4
dcterms.source.startPage106121
dcterms.source.issn0924-8579
dcterms.source.titleInternational Journal of Antimicrobial Agents
dc.date.updated2020-10-06T05:35:04Z
curtin.departmentSchool of Pharmacy and Biomedical Sciences
curtin.accessStatusOpen access
curtin.facultyFaculty of Health Sciences
curtin.contributor.orcidRamsay, Josh [0000-0002-1301-7077]
dcterms.source.eissn1872-7913
curtin.contributor.scopusauthoridRamsay, Josh [8529700000]


Files in this item

Thumbnail
Name:
Fos_Mowlaboccus_Accepted_onlin ...
Size:
588.4Kb
Format:
PDF
Thumbnail
Name:
81418.pdf
Size:
620.0Kb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record

http://creativecommons.org/licenses/by-nc-nd/4.0/
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0/