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dc.contributor.authorSheng, H.Z.
dc.contributor.authorMartenson, R.E.
dc.contributor.authorGrgacic, E.V.
dc.contributor.authorDowse, Carol
dc.contributor.authorCarnegie, R.L.
dc.contributor.authorBernard, C.C.A.
dc.date.accessioned2020-10-26T03:48:52Z
dc.date.available2020-10-26T03:48:52Z
dc.date.issued1988
dc.identifier.citationSheng, H.Z. and Martenson, R.E. and Grgacic, E.V. and Dowse, C.A. and Carnegie, R.L. and Bernard, C.C.A. 1988. Electroimmunoblotting of myelin basic protein peptides: a novel approach to the rapid characterisation of antigenic specificities of monoclonal and polyclonal anti-MBP antibodies. Journal of Neuroimmunology. 17 (3): pp. 183-192.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/81499
dc.identifier.doi10.1016/0165-5728(88)90066-5
dc.description.abstract

A rapid and sensitive method for the identification of antigenic determinants recognised by monoclonal and polyclonal antibodies directed against myelin basic protein (MBP) is described. By electroimmunoblotting a series of overlapping peptides covering the entire MBP molecule with monoclonal anti-MBP antibodies, the binding pattern of immunoreactive peptides can be rapidly determined and the reactive antigenic determinant identified. This procedure, which can be performed with both native and synthetic peptides, can also with appropriate modification, be applied to the analysis of naturally occuring or experimentally induced polyclonal anti-MBP autoantibodies. © 1988.

dc.languageEnglish
dc.publisherElsevier
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectImmunology
dc.subjectNeurosciences
dc.subjectNeurosciences & Neurology
dc.titleElectroimmunoblotting of myelin basic protein peptides: a novel approach to the rapid characterisation of antigenic specificities of monoclonal and polyclonal anti-MBP antibodies
dc.typeJournal Article
dcterms.source.volume17
dcterms.source.number3
dcterms.source.startPage183
dcterms.source.endPage192
dcterms.source.issn0165-5728
dcterms.source.titleJournal of Neuroimmunology
dc.date.updated2020-10-26T03:48:51Z
curtin.accessStatusFulltext not available
curtin.facultyFaculty of Business and Law
curtin.contributor.orcidDowse, Carol [0000-0001-8295-7946]
dcterms.source.eissn1872-8421
curtin.contributor.scopusauthoridDowse, Carol [6602559076]


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