Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    The Cost-Utility of Magnetic Resonance Imaging for Breast Cancer in BRCA1 Mutation Carriers Aged 30–49

    Access Status
    Fulltext not available
    Authors
    Norman, Richard
    Evans, D.
    Easton, D.
    Young, K.
    Date
    2007
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Norman, R. and Evans, D. and Easton, D. and Young, K. 2007. The Cost-Utility of Magnetic Resonance Imaging for Breast Cancer in BRCA1 Mutation Carriers Aged 30–49. The European Journal of Health Economics. 8: pp. 137-144.
    Source Title
    The European Journal of Health Economics
    DOI
    10.1007/s10198-007-0042-9
    Additional URLs
    http://www.springer.com/economics/policy/journal/10198
    ISSN
    1618-7598
    URI
    http://hdl.handle.net/20.500.11937/8246
    Collection
    • Curtin Research Publications
    Abstract

    Recent evidence has investigated the costeffectiveness of magnetic resonance imaging (MRI) in younger women with a BRCA1 mutation. However, this evidence has not been contrasted with existing cost-effectiveness standards to determine whether screening is appropriate, given limited societal resources. We constructed a Markov model investigating surveillance tools (mammography, MRI, both in parallel) under a National Health Service (NHS) perspective. The key benefit of MRI is that increased sensitivity leads to early detection, and improved prognosis. For a 30- to 39-year-old cohort, the cost per quality-adjusted life year (QALY) of mammography relative to no screening was £5,200. The addition of MRI to this costs £13,486 per QALY. For a 40- to 49-year-old cohort, the corresponding values were £2,913 and £7,781. Probabilistic sensitivity analysis supported the cost-effectiveness of the parallel approach of mammography and MRI. It is necessary to extend this analysis beyond BRCA1 carriers within this age group, and also to other age groups.

    Related items

    Showing items related by title, author, creator and subject.

    • Treatment-focused DNA testing for newly diagnosed breast cancer patients: some implications for clinical practice
      Lobb, Elizabeth; Barlow-Stewart, K.; Suthers, G.; Hallowell, N. (2010)
      There is accumulating evidence that women with breast cancer due to a familial BRCA1 or BRCA2 mutation benefit from specific surgical and chemotherapeutic treatment strategies. However, the rapid identification of such ...
    • European radiographers’ challenges from mammography education and clinical practice – an integrative review
      Metsälä, E.; Meystre, N.; Jorge, J.; Henner, A.; Kukkes, T.; Sá dos Reis, Claudia (2017)
      Objectives: This study aims to identify European radiographers’ challenges in clinical performance in mammography and the main areas of mammography that require more and better training. Methods: An extensive search was ...
    • Mammography equipment design: impact on radiographers’ practice
      Costa, S.; Oliveira, E.; Reis, Claudia; Viegas, S.; Serranheira, F. (2014)
      Objectives: Identify radiographers’ postures during frequent mammography procedures related to the mammography equipment and patient characteristics. Methods: A postural task analysis was performed using images acquired ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.