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    Multiscale characterisation of Achilles tendons during mechanical loading

    Al Makhzoomi A 2020.pdf (7.248Mb)
    Access Status
    Open access
    Authors
    Al Makhzoomi, Anas Khalaf
    Date
    2020
    Supervisor
    Garry Allison
    Brett Kirk
    Jian-Ping Wu
    Type
    Thesis
    Award
    PhD
    
    Metadata
    Show full item record
    Faculty
    Health Sciences
    School
    Curtin Graduate Research School
    URI
    http://hdl.handle.net/20.500.11937/82466
    Collection
    • Curtin Theses
    Abstract

    Although mechanical loading correlate to multi-hierarchical changes, the multiscale response during tendon damage remains not yet fully understood. Therefore, this thesis assessed the multiscale structure-function mechanisms in response to different levels and durations of strains in GAG and un/depleted Achilles tendons. At the nano/macroscales, increased levels and durations of strains resulted in increased changes in form and function. This thesis identifies a variety of multiscale properties that may contribute to the understanding of the mechanism of tendon pathology.

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