The chiasm: Transfusion practice versus patient blood management
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In recent years it became increasingly clear that allogeneic redblood cell (RBC) transfusions result in increased mortality andmajor adverse clinical outcomes. The major risk factors for RBCtransfusions are preoperative anaemia, high perioperative bloodloss and liberal transfusion triggers. Patient blood management(PBM), the bundle of preoperative anaemia treatment, measures toreduce perioperative blood loss and optimising anaemia tolerance,aims at minimising RBC transfusion needs and improving clinicaloutcomes. PBM has been adopted by the World Health Organizationas the new standard of care and all member states are urgedto implement this concept. Australia is leading the world in thatPBM is indeed implemented at the current time.
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Hofmann, Axel; Farmer, Shannon; Towler, Simon (2012)Purpose of review: Evidence-based patient blood management (PBM) is aimed at achieving better patient outcomes by relying on a patient's own blood rather than on donor blood. This review covers the rationale behind PBM, ...
Gender disparities in red blood cell transfusion in elective surgery: a post hoc multicentre cohort studyGombotz, H.; Schreier, G.; Neubauer, S.; Kastner, P.; Hofmann, Axel (2016)Objectives: A post hoc gender comparison of transfusion-related modifiable risk factors among patients undergoing elective surgery. Settings: 23 Austrian centres randomly selected and stratified by region and level of ...
Ranucci, M.; Aronson, S.; Dietrich, W.; Dyke, C.; Hofmann, Axel; Karkouti, K.; Levi, M.; Murphy, G.; Sellke, F.; Shore-Lesserson, L.; von Heymann, C. (2011)Transfusion of allogeneic blood products during and aftercardiac operations is common. When the degree of anemiaand the consequent decrease in oxygen deliverylead to organ ischemia, there is little doubt that red bloodcell ...