Trimethylamine N-oxide (TMAO): a new attractive target to decrease cardiovascular risk.
MetadataShow full item record
Cardiovascular disease (CVD) is one of the greatest disease burdens and takes the lives of many each year. There are many risk factors both modifiable and non-modifiable which contribute to the onset and progression of the disease. Trimethylamine N-oxide (TMAO) in recent years has been found to have a correlation with CVD onset. Those with increased levels of the metabolite have a markedly increased risk of future development of cardiometabolic disorders.This literature review aimed to critique past studies undertaken to find a consensus of the significance of the interrelationship between TMAO and cardiovascular risk. A definite link between TMAO levels and a CVD outcome was found. The majority of the literature stated the relationship with evidence; however, there is still some uncertainty as to why and how the correlation occurs. Further study needs to be done to further dissect and understand the relationship between TMAO and CVD risk.
Showing items related by title, author, creator and subject.
TNF block haplotypes reveal diverse pathways between TNF and disease: Implications for understanding neuropathy in HIV patientsChew, C.; Valente, F.; Wallace, H.; Tan, J.; Temple, S.; Price, Patricia (2012)The region spanning the tumor necrosis factor (TNF) cluster in the human major histocompatibility complex (MHC) has been implicated in susceptibility to numerous immunopathological and inflammatory diseases. However, ...
Perkovic, V.; Verdon, C.; Ninomiya, T.; Barzi, F.; Cass, A.; Patel, A.; Jardine, M.; Gallagher, M.; Turnbull, F.; Chalmers, J.; Craig, J.; Huxley, Rachel (2008)Background: Markers of kidney dysfunction such as proteinuria or albuminuria have been reported to be associated with coronary heart disease, but the consistency and strength of any such relationship has not been clearly ...
Effectiveness of general practice nurse interventions in cardiac risk factor reduction amongst adultsHalcomb, E.; Moujalli, S.; Griffiths, R.; Davidson, Patricia (2007)Background: Cardiovascular disease is the leading cause of death for adults in Australia. In recent years there has been a shift in health service delivery from institutional to community-based care for chronic conditions, ...