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dc.contributor.authorSwanepoel, Ione
dc.contributor.authorRoberts, April
dc.contributor.authorBrauns, Chelsea
dc.contributor.authorChaliha, Devahuti R
dc.contributor.authorPapa, Veronica
dc.contributor.authorPalmer, Raymond D
dc.contributor.authorVaccarezza, Mauro
dc.date.accessioned2021-04-07T05:44:05Z
dc.date.available2021-04-07T05:44:05Z
dc.date.issued2021
dc.identifier.citationSwanepoel, I. and Roberts, A. and Brauns, C. and Chaliha, D.R. and Papa, V. and Palmer, R.D. and Vaccarezza, M. 2021. Trimethylamine N-oxide (TMAO): a new attractive target to decrease cardiovascular risk. Postgrad Med J.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/83145
dc.identifier.doi10.1136/postgradmedj-2021-139839
dc.description.abstract

Cardiovascular disease (CVD) is one of the greatest disease burdens and takes the lives of many each year. There are many risk factors both modifiable and non-modifiable which contribute to the onset and progression of the disease. Trimethylamine N-oxide (TMAO) in recent years has been found to have a correlation with CVD onset. Those with increased levels of the metabolite have a markedly increased risk of future development of cardiometabolic disorders.This literature review aimed to critique past studies undertaken to find a consensus of the significance of the interrelationship between TMAO and cardiovascular risk. A definite link between TMAO levels and a CVD outcome was found. The majority of the literature stated the relationship with evidence; however, there is still some uncertainty as to why and how the correlation occurs. Further study needs to be done to further dissect and understand the relationship between TMAO and CVD risk.

dc.languageeng
dc.subjectadult cardiology
dc.subjectbiophysics
dc.subjectcoronary heart disease
dc.subjectmicrobiology
dc.subjectpathology
dc.subjectvascular medicine
dc.titleTrimethylamine N-oxide (TMAO): a new attractive target to decrease cardiovascular risk.
dc.typeJournal Article
dcterms.source.issn0032-5473
dcterms.source.titlePostgrad Med J
dc.date.updated2021-04-07T05:44:04Z
curtin.departmentCurtin Medical School
curtin.accessStatusIn process
curtin.accessStatusIn process
curtin.facultyFaculty of Health Sciences
curtin.contributor.orcidVaccarezza, Mauro [0000-0003-3060-318X]
dcterms.source.eissn1469-0756
curtin.contributor.scopusauthoridVaccarezza, Mauro [6701350504]


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