Association of host transcriptomic and microbiome profiles with food allergy
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This thesis explores the molecular mechanism of food allergy among children in Perth, Australia. The overall aim of this thesis is to systematically elucidate the association of gene expression and microbiome with the pathogenesis of food allergy. The results of this thesis contribute towards a greater understanding of mechanisms underlying food allergy and may have utility in providing targets or biomarkers for better prediction and early identification of food allergy.
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Lee, K.; Song, Y.; O'Sullivan, M.; Pereira, Gavin; Loh, R.; Zhang, G. (2017)Food allergy is a major clinical and public health concern worldwide. The risk factors are well defined, however, the mechanisms by which they affect immune development remain largely unknown, and unfortunately the effective ...
Poole, A.; Song, Yong; Brown, H.; Hart, P.; Zhang, Guicheng (2018)© 2018 Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine. Food allergies are becoming increasingly prevalent, especially in young children. ...
Lee, Khui Hung; Song, Yong; Wu, W.; Yu, K.; Zhang, Guicheng (2020)Food allergy appears to have its roots in an insufficient exposure to a diverse range of environmental microbiota during early life. Microbial exposure ensures the colonization of the gastrointestinal tract with commensal ...