Attenuation of chronic tension headache frequency and severity with daily l-arginine and aged garlic extract dietary supplementation
MetadataShow full item record
A 74-year-old female subject with suboptimal management of episodic tension headache was treated with a daily dose of 1.5 g l-arginine and 1.2 g aged garlic extract (AGE). The aim of the intervention was to promote vasodilation of parenchymal cerebral blood vessels. Within 6 weeks of commencing treatment, her self-reported symptoms improved markedly and were sustained at 2 years following commencement. We propose that the putative beneficial effect of l-arginine and AGE in this patient is because of the well-established systemic vasodilatory effects of l-arginine and aged garlic extract. On the hypothesis that migraine is precipitated by cerebral microvascular constriction, we recommend a double-blind randomised controlled trial to clinically test this hypothesis in migraine patients.
Showing items related by title, author, creator and subject.
L-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challengeKrause, M.; McClenaghan, N.; Flatt, P.; Hamem de Bittencourt, P.; Murphy, C.; Newsholme, Philip (2011)In this work, our aim was to determine whether L-arginine (a known insulinotropic amino acid) can promote a shift of β-cell intermediary metabolism favoring glutathione (GSH) and glutathione disulfide (GSSG) antioxidant ...
Elevated levels of branched-chain amino acids have little effect on pancreatic islet cells, but L-arginine impairs function through activation of the endoplasmic reticulum stress responseMullooly, N.; Vernon, W.; Smith, D.; Newsholme, Philip (2014)New Findings - What is the central question of this study?: Recent studies have demonstrated strong correlations between circulating branched-chain amino acid (AA) levels and insulin resistance, a predictor of susceptibility ...
Chemat, F.; Anjum, H.; Shariff, A.; Perumal, Kumar; Murugesan, T. (2016)In the present work, a common amino acid, l-arginine (0.05, 0.10, 0.15 and 0.20 mol) was added to (Choline chloride + urea) to form ternary deep eutectic solvents. The thermal properties namely, melting point, glass ...