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dc.contributor.authorRamzy, J.
dc.contributor.authorAndrianopoulos, N.
dc.contributor.authorRoberts, L.
dc.contributor.authorDuffy, S.J.
dc.contributor.authorClark, D.
dc.contributor.authorTeh, A.W.
dc.contributor.authorAjani, A.E.
dc.contributor.authorReid, Christopher
dc.contributor.authorBrennan, A.
dc.contributor.authorFreeman, M.
dc.date.accessioned2023-08-31T03:46:15Z
dc.date.available2023-08-31T03:46:15Z
dc.date.issued2019
dc.identifier.citationRamzy, J. and Andrianopoulos, N. and Roberts, L. and Duffy, S.J. and Clark, D. and Teh, A.W. and Ajani, A.E. et al. 2019. Outcomes in patients with peripheral vascular disease following percutaneous coronary intervention. Catheterization and Cardiovascular Interventions. 94 (4): pp. 588-597.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/93107
dc.identifier.doi10.1002/ccd.28145
dc.description.abstract

Objectives: To evaluate the clinical characteristics and outcomes of patients with peripheral vascular disease (PVD) undergoing percutaneous coronary intervention (PCI) in a contemporary setting, and to determine whether use of drug-eluting stents (DESs) improves outcomes. Background: PVD was an independent risk factor for adverse outcomes following PCI in the bare-metal stent (BMS) era. It is not known whether outcomes in these patients have improved with advances in interventional techniques and stent technology, as they have for the general population. Methods: Eighteen thousand three hundred and eighty patients undergoing PCI from an Australian registry between 2005 and 2013 were studied. Clinical and procedural data, 30-day and 12-month outcomes were compared in those with and without a reported history of PVD. Outcomes were also compared between patients with PVD who received DES and those who received BMS. Long-term mortality was compared using Australian National Death Index (NDI) linkage. Results: Patients with PVD (n = 1,251, 6.8%) were older and had more prevalent diabetes, hypertension, cerebrovascular disease, heart failure, renal impairment, ostial lesions, left main, and multi-vessel disease (p < 0.001). Patients with PVD had significantly higher rates of major adverse cardiovascular events (MACEs) compared with those without PVD, in-hospital (5.7% vs. 4.1%, p < 0.008), at 30-days (8.6% vs. 5.8%, p < 0.001) and at 12-months (24.6% vs. 13.2%, p < 0.001). At 4.9 ± 2.6 years follow-up, there was significantly greater mortality in the PVD group. PVD patients who received DES experienced significantly less MACE than PVD patients treated with BMS at 30-days (4.8 vs. 10.1%, p < 0.001) and 12-months (19.4 vs. 26.4%, p < 0.005). Conclusions: PVD is an independent predictor of adverse outcomes in patients undergoing PCI. PVD patient who received DES had improved outcomes compared with those receiving BMS.

dc.languageEnglish
dc.publisherWILEY
dc.relation.sponsoredbyhttp://purl.org/au-research/grants/nhmrc/1111170
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectCardiac & Cardiovascular Systems
dc.subjectCardiovascular System & Cardiology
dc.subjectcoronary artery disease
dc.subjectperipheral arterial disease
dc.subjectrevascularization
dc.subjectDRUG-ELUTING STENTS
dc.subjectLONG-TERM OUTCOMES
dc.subjectACUTE MYOCARDIAL-INFARCTION
dc.subjectARTERIAL-DISEASE
dc.subjectCLINICAL-OUTCOMES
dc.subjectTASK-FORCE
dc.subjectMORTALITY
dc.subjectIMPACT
dc.subjectASSOCIATION
dc.subjectPREDICTORS
dc.subjectcoronary artery disease
dc.subjectperipheral arterial disease
dc.subjectrevascularization
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectComorbidity
dc.subjectCoronary Artery Disease
dc.subjectDrug-Eluting Stents
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMetals
dc.subjectMiddle Aged
dc.subjectPercutaneous Coronary Intervention
dc.subjectPeripheral Vascular Diseases
dc.subjectProsthesis Design
dc.subjectRegistries
dc.subjectRetrospective Studies
dc.subjectRisk Assessment
dc.subjectRisk Factors
dc.subjectStents
dc.subjectTime Factors
dc.subjectTreatment Outcome
dc.subjectVictoria
dc.subjectMelbourne Interventional Group (MIG)
dc.subjectHumans
dc.subjectPeripheral Vascular Diseases
dc.subjectMetals
dc.subjectTreatment Outcome
dc.subjectRegistries
dc.subjectRisk Assessment
dc.subjectRisk Factors
dc.subjectRetrospective Studies
dc.subjectProsthesis Design
dc.subjectStents
dc.subjectComorbidity
dc.subjectTime Factors
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectMiddle Aged
dc.subjectVictoria
dc.subjectFemale
dc.subjectMale
dc.subjectCoronary Artery Disease
dc.subjectDrug-Eluting Stents
dc.subjectPercutaneous Coronary Intervention
dc.titleOutcomes in patients with peripheral vascular disease following percutaneous coronary intervention
dc.typeJournal Article
dcterms.source.volume94
dcterms.source.number4
dcterms.source.startPage588
dcterms.source.endPage597
dcterms.source.issn1522-1946
dcterms.source.titleCatheterization and Cardiovascular Interventions
dc.date.updated2023-08-31T03:46:15Z
curtin.note

This is the peer reviewed version of the following article: Ramzy, J, Andrianopoulos, N, Roberts, L, et al. Outcomes in patients with peripheral vascular disease following percutaneous coronary intervention. Catheter Cardiovasc Interv. 2019; 94: 588–597, which has been published in final form at https://doi.org/10.1002/ccd.28145. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.

curtin.departmentCurtin School of Population Health
curtin.accessStatusOpen access
curtin.facultyFaculty of Health Sciences
curtin.contributor.orcidReid, Christopher [0000-0001-9173-3944]
dcterms.source.eissn1522-726X
curtin.repositoryagreementV3


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