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dc.contributor.authorNg, L.Y.
dc.contributor.authorHowarth, T.P.
dc.contributor.authorDoss, Arockia
dc.contributor.authorCharakidis, M.
dc.contributor.authorKaranth, N.V.
dc.contributor.authorMo, L.
dc.contributor.authorHeraganahally, S.S.
dc.date.accessioned2025-05-08T17:52:42Z
dc.date.available2025-05-08T17:52:42Z
dc.date.issued2024
dc.identifier.citationNg, L.Y. and Howarth, T.P. and Doss, A.X. and Charakidis, M. and Karanth, N.V. and Mo, L. and Heraganahally, S.S. 2024. Significance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study. Journal of Medical Radiation Sciences. 71 (3): pp. 365-374.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/97701
dc.identifier.doi10.1002/jmrs.783
dc.description.abstract

Introduction: There are limited data on chest computed tomography (CT) findings in the assessment of lung nodules among adult Aboriginal Australians. In this retrospective study, we assessed lung nodules among a group of adult Aboriginal Australians in the Northern Territory of Australia. Methods: Patients who underwent at least two chest CT scans between 2012 and 2020 among those referred to undergo lung function testing (spirometry) were included. Chest CT scans were assessed for the number, location, size and morphological characteristics of lung nodules. Results: Of the 402 chest CTs assessed, 75 patients (18.7%) had lung nodules, and 57 patients were included in the final analysis with at least two CT scans available for assessment over a median follow-up of 87 weeks. Most patients (68%) were women, with a median age of 58 years and smoking history in 83%. The majority recorded only a single nodule 43 (74%). Six patients (10%) were diagnosed with malignancy, five with primary lung cancer and one with metastatic thyroid cancer. Of the 51 (90%) patients assessed to be benign, 64 nodules were identified, of which 25 (39%) resolved, 38 (59%) remained stable and one (1.8%) enlarged on follow-up. Nodules among patients with malignancy were typically initially larger and enlarged over time, had spiculated margins and were solid, showing no specific lobar predilection. Conclusions: Most lung nodules in Aboriginal Australians are likely to be benign. However, a proportion could be malignant. Further prospective studies are required for prognostication and monitoring of lung nodules in this population.

dc.languageeng
dc.subjectFirst Nations
dc.subjectIndigenous
dc.subjectlung cancer
dc.subjectmalignancy
dc.subjectpulmonary
dc.subjectradiology
dc.subjectrespiratory
dc.subjectAdult
dc.subjectAged
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectAustralia
dc.subjectAustralian Aboriginal and Torres Strait Islander Peoples
dc.subjectLung Neoplasms
dc.subjectRetrospective Studies
dc.subjectTomography, X-Ray Computed
dc.subjectHumans
dc.subjectLung Neoplasms
dc.subjectTomography, X-Ray Computed
dc.subjectRetrospective Studies
dc.subjectAdult
dc.subjectAged
dc.subjectMiddle Aged
dc.subjectAustralia
dc.subjectFemale
dc.subjectMale
dc.subjectAustralian Aboriginal and Torres Strait Islander Peoples
dc.titleSignificance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study
dc.typeJournal Article
dcterms.source.volume71
dcterms.source.number3
dcterms.source.startPage365
dcterms.source.endPage374
dcterms.source.issn2051-3895
dcterms.source.titleJournal of Medical Radiation Sciences
dc.date.updated2025-05-08T17:52:41Z
curtin.departmentCurtin Medical School
curtin.accessStatusIn process
curtin.facultyFaculty of Health Sciences
curtin.contributor.orcidDoss, Arockia [0000-0001-9171-4364]
dcterms.source.eissn2051-3909
curtin.repositoryagreementV3


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