Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Understanding the long-term impacts of burn on the cardiovascular system

    237565_237565.pdf (285.5Kb)
    Access Status
    Open access
    Authors
    Duke, J.
    Randall, Sean
    Fear, M.
    Boyd, James
    Rea, S.
    Wood, F.
    Date
    2015
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Duke, J. and Randall, S. and Fear, M. and Boyd, J. and Rea, S. and Wood, F. 2015. Understanding the long-term impacts of burn on the cardiovascular system. Burns. 42 (2): pp. 366-374.
    Source Title
    Burns
    DOI
    10.1016/j.burns.2015.08.020
    ISSN
    0305-4179
    School
    Centre for Population Health Research
    URI
    http://hdl.handle.net/20.500.11937/11558
    Collection
    • Curtin Research Publications
    Abstract

    Background: Whilest the most obvious impact of burn is on the skin, systemic responses also occur after burn that lead to wide-spread changes to the body, including the heart. The aim of this study was to assess if burn in mid-aged and older adults is associated with increased long-term admissions and death due to diseases of the circulatory system. Methods: A population-based longitudinal study using linked hospital morbidity and death data from Western Australia was undertaken of adults aged at least 45 years when hospitalized for a first burn (n = 6004) in 1980-2012 and a frequency matched non-injury comparison cohort, randomly selected from Western Australia's electoral roll (n = 22,673). Crude admission rates and cumulative length of stay for circulatory diseases were calculated. Negative binomial and Cox proportional hazards regression modelling were used to generate incidence rate ratios (IRR) and hazard ratios (HR), respectively. HR was used as a measure of the mortality rate ratio (MRR). Results: After adjustment for demographic factors and pre-existing health status, the burn cohort had 1.46 times (95% confidence interval (CI): 1.36-1.56) as many admissions and almost three times the number of days in hospital with a circulatory system diagnosis (IRR, 95%CI: 2.90, 2.60-3.25) than the uninjured cohort for circulatory diseases. The burn cohort had higher admission rates for ischaemic heart disease (IRR, 95%CI: 1.21, 1.07-1.36), heart failure (IRR, 95%CI: 2.29, 1.85-2.82) and cerebrovascular disease (IRR, 95%CI: 1.57, 1.33-1.84). The burn cohort was found to have increased long-term mortality caused by circulatory system diseases (MRR, 95%CI: 1.11, 1.02-1.20). Conclusions: Findings of increased hospital admission rates, prolonged length of hospital stay and increased long-term mortality related to circulatory system diseases in the burn cohort provide evidence to support that burn has long-lasting systemic impacts on the heart and circulation.

    Related items

    Showing items related by title, author, creator and subject.

    • Long-term Effects of Pediatric Burns on the Circulatory System.
      Duke, J.; Randall, S.; Fear, M.; Boyd, James; Rea, S.; Wood, F. (2015)
      BACKGROUND: The systemic responses to burns (in particular, elevated levels of catecholamines and stress hormones) have been shown to have an impact on cardiac function for at least 3 years in children with burns. However, ...
    • A retrospective cohort study to compare post-injury admissions for infectious diseases in burn patients, non-burn trauma patients and uninjured people
      Duke, J.; Randall, Sean; Boyd, J.; Fear, M.; Rea, S.; Wood, F. (2018)
      Background: Injury triggers a range of systemic effects including inflammation and immune responses. This study aimed to compare infectious disease admissions after burn and other types of injury using linked hospital ...
    • Burns and long-term infectious disease morbidity: A population-based study
      Duke, J.; Randall, Sean; Wood, F.; Boyd, James H.; Fear, M. (2016)
      Background: There is a growing volume of data that indicates that serious injury suppresses immune function, predisposing individuals to infectious complications. With recent evidence showing long-term immune dysfunction ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.