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    Long-term mortality among older adults with burn injury: a population-based study in Australia

    Access Status
    Open access via publisher
    Authors
    Duke, Janine
    Boyd, James
    Rea, S.
    Randall, Sean
    Wood, Fiona
    Date
    2015
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Duke, J. and Boyd, J. and Rea, S. and Randall, S. and Wood, F. 2015. Long-term mortality among older adults with burn injury: a population-based study in Australia. Bulletin of the World Health Organisation. 93: pp. 400-406.
    Source Title
    Bulletin of the World Health Organisation
    DOI
    10.2471/BLT.14.149146
    ISSN
    0042-9686
    URI
    http://hdl.handle.net/20.500.11937/11966
    Collection
    • Curtin Research Publications
    Abstract

    Objective To assess if burn injury in older adults is associated with changes in long-term all-cause mortality and to estimate the increased risk of death attributable to burn injury. Methods We conducted a population-based matched longitudinal study – based on administrative data from Western Australia’s hospital morbidity data system and death register. A cohort of 6014 individuals who were aged at least 45 years when hospitalized for a first burn injury in 1980–2012 was identified. A non-injury comparison cohort, randomly selected from Western Australia’s electoral roll (n = 25 759), was matched to the patients. We used Kaplan–Meier plots and Cox proportional hazards regression to analyse the data and generated mortality rate ratios and attributable risk percentages. Findings For those hospitalized with burns, 180 (3%) died in hospital and 2498 (42%) died after discharge. Individuals with burn injury had a 1.4-fold greater mortality rate than those with no injury (95% confidence interval, CI: 1.3–1.5). In this cohort, the long-term mortality attributable to burn injury was 29%. Mortality risk was increased by both severe and minor burns, with adjusted mortality rate ratios of 1.3 (95% CI: 1.1–1.9) and 2.1 (95% CI: 1.9–2.3), respectively. Conclusion Burn injury is associated with increased long-term mortality. In our study population, sole reliance on data on in-hospital deaths would lead to an underestimate of the true mortality burden associated with burn injury.

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      Background: Burn injury initiates an acute inflammatory response that subsequently drives wound repair. However, acute disruption to the immune response is also common, leading to susceptibility to sepsis and increased ...
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