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dc.contributor.authorSun, Zhonghua
dc.contributor.authorNg, Curtise
dc.identifier.citationSun, Zhonghua and Ng, Curtise. 2010. Dual-source CT Angiography in Aortic Stent Grafting: An in vitro Aorta Phantom Study of Image Noise and Radiation Dose. Academic Radiology. 17 (7): pp. 884-893.

Rationale and Objectives: The aim of the study was to investigate the optimal protocols of dual-source computed tomography (CT) angiographyin aortic stent grafting in terms of image noise and radiation dose, based on an in vitro phantom study. Materials and Methods: A series of helical CT cans were performed on a human aorta phantom using a dual-source CT scannerwith kVp of 100, 120, and 140, corresponding mAs of 180, 150, and 100; slice thickness of 1.0, 1.5, and 2.0 mm; and pitch value of 0.5, 1.0, and 1.5, respectively. Image quality was determined by measuring the standard deviation (SD) on three-dimensional virtual intravascular endoscopy (VIE) images. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were measured on two dimensional(2D) axial images at superior mesenteric artery (SMA), renal arteries, and aneurysm. Effective dose was determined based on dose-length product.Results: SD measured on VIE images was independent of kVp and pitch values but was determined by the slice thickness (P <.05) at the SMA and renal arteries. SNR and CNR measured on 2D images showed significant differences between variable kVp values and slice thicknesses (P <.05), but were independent of pitch values. The mean estimated effective dose for 120 kVp and 140 kVp protocols were 2.66 ± 0.21 mSv and 2.68 ± 0.18 mSv, respectively. The mean estimated effective dose for 100 kVp protocol was significantly lower (1.97 ± 0.07 mSv, P < .0001). This indicates a reduction of 26.5% radiation dose when the kVp was lowered from 140 to 100. Conclusion: A scanning protocol of 1.5-mm slice thickness, pitch 1.5 with 100 kVp, and 180 mAs is recommended for a dual-source CT angiography in aortic stent grafting as it leads to significant reduction of radiation dose while achieving diagnostic images.

dc.publisherElsevier Ltd
dc.subjectvirtual intravascular endoscopy
dc.subjectimage noise
dc.subject3D visualization
dc.subjectradiation dose
dc.subjectaortic stent graft
dc.subjectMultislice CT
dc.titleDual-source CT Angiography in Aortic Stent Grafting: An in vitro Aorta Phantom Study of Image Noise and Radiation Dose
dc.typeJournal Article
dcterms.source.titleAcademic Radiology

The link to the journal’s home page is: Copyright © 2010 Elsevier B.V. All rights reserved

curtin.departmentDepartment of Imaging and Applied Physics
curtin.accessStatusOpen access

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