Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Prediction of outcome following hypoxia/ischaemia in the human infant using cerebral impedance

    Access Status
    Fulltext not available
    Authors
    Lingwood, B.
    Healy, Genevieve
    Kecskes, Z.
    Dunster, K.
    Gray, P.
    Ward, L.
    Colditz, P.
    Date
    2009
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Lingwood, B. and Healy, G. and Kecskes, Z. and Dunster, K. and Gray, P. and Ward, L. and Colditz, P. 2009. Prediction of outcome following hypoxia/ischaemia in the human infant using cerebral impedance. Clinical Neurophysiology. 120 (2): pp. 225-230.
    Source Title
    Clinical Neurophysiology
    DOI
    10.1016/j.clinph.2008.11.008
    ISSN
    1388-2457
    School
    School of Physiotherapy and Exercise Science
    URI
    http://hdl.handle.net/20.500.11937/2759
    Collection
    • Curtin Research Publications
    Abstract

    Objective: Changes in cerebral impedance in the newborn piglet are able to discriminate, within 1-2 h of acute hypoxia, between animals which will have a good neurological outcome, and those who have suffered more severe hypoxia resulting in poor outcome. The aim of this study was to determine if cerebral impedance could be used to identify those human infants with an encephalopathy following acute hypoxia who subsequently have a poor neurological outcome. It is these infants who may benefit most from neural rescue treatment. Methods: Twenty-four newborn term infants with evidence of severe acute intrapartum hypoxia and encephalopathy were studied. Bioimpedance spectroscopy was commenced as soon as possible after birth and repeated every 30 min until the infant was 12 h old. Neurodevelopmental outcome was assessed at 12 months of age. Results: Although cerebral impedance was different to control values, there was no significant difference in cerebral impedance between hypoxic babies with normal and those with abnormal development. Conclusion: Cerebral impedance was increased in hypoxic babies, as predicted from animal data, but the method was not suitable for discrimination of outcome. Significance: Cerebral impedance is not useful for early identification of infants who subsequently have a poor outcome after acute intrapartum hypoxia and who may benefit from neural rescue treatment. © 2008 International Federation of Clinical Neurophysiology.

    Related items

    Showing items related by title, author, creator and subject.

    • Oscillations in cardiovascular function during acute hypoxia in the newborn piglet are associated with less neurological damage and occur more frequently in females
      Harris, T.; Healy, Genevieve; Colditz, P.; Lingwood, B. (2009)
      The function of the cardiovascular system during hypoxia is an important determinant of neurologic outcome. Oscillations in blood pressure, particularly type-3 waves with a duration of 10 to 160 s, have been shown to occur ...
    • Associations between serum cortisol, cardiovascular function and neurological outcome following acute global hypoxia in the newborn piglet
      Harris, T.; Healy, Genevieve; Colditz, P.; Lingwood, B. (2009)
      Perinatal asphyxia is a significant contributor to neonatal brain injury. However, there is significant variability in neurological outcome in neonates after global hypoxiaischemia. The aims of this study were to identify ...
    • Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants
      Spittle, A.; Orton, J.; Anderson, P.; Boyd, Roslyn; Doyle, L. (2015)
      Background: Infants born preterm are at increased risk of developing cognitive and motor impairment compared with infants born at term. Early developmental interventions have been provided in the clinical setting with the ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.