Preliminary CFD simulation of mixing in bioreactor agitated by Rushton turbine
MetadataShow full item record
Computational fluid dynamics (CFD) is a handy tool in the study of mixing problems in bioreactor dealing with ethanolic fermentation process. Due to the complexity of the bioreactor performance which involves microbial activities throughout the fermentation process, ideally mixed assumption is considered. However, in reality, the mixing mechanism of bioreactor is not perfectly mixed. In this study, the non-ideally mixed mechanism of bioreactor is described with the implementation of aeration rate and stirrer speed in the Herbert’s kinetics model. The proposed kinetics model is implemented into CFD to observe the mixing mechanism of bioreactor. CFD results show that the proposed kinetics hybrid model successfully captured the mixing mechanism of the bioreactor. In addition to that, the proposed kinetics model could predict the ethanol concentration produced throughout the fermentation process. These results show the importance of implementing non-ideally mixed behaviour in the prediction of the bioreactor performance.
Showing items related by title, author, creator and subject.
Liew, Emily Wan Teng (2011)Mixing plays a substantial role in determining the overall performance of a bioreactor. Well mixing in bioreactor, especially for ethanolic fermentation process is important for the homogenization of miscible and immiscible ...
Liew, Emily; Nandong, Jobrun; Samyudia, Yudi (2013)Process models play an important role in the bioreactor design, optimisation and control. In previous work, the bioreactor models have mainly been developed by considering the microbial kinetics and the reactor environmental ...
Liew, Emily; Kumar, Perumal; Samyudia, Yudi (2009)In this paper, we address the progress, challenges and prospect of modeling mixing in bioreactor by the utilization of Computational Fluid Dynamics (CFD). Efficient operation of bioreactor is essential in the biotechnological ...