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dc.contributor.authorMonecke, S.
dc.contributor.authorCoombs, Geoffrey
dc.contributor.authorPearson, J.
dc.contributor.authorHotzel, H.
dc.contributor.authorSlickers, P.
dc.contributor.authorEhricht, R.
dc.date.accessioned2017-01-30T13:25:49Z
dc.date.available2017-01-30T13:25:49Z
dc.date.created2015-12-10T04:26:07Z
dc.date.issued2015
dc.identifier.citationMonecke, S. and Coombs, G. and Pearson, J. and Hotzel, H. and Slickers, P. and Ehricht, R. 2015. A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element. Antimicrobial Agents and Chemotherapy. 59 (11): pp. 7142-7144.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/31513
dc.identifier.doi10.1128/AAC.01745-15
dc.description.abstract

Copyright © 2015, American Society for Microbiology. All Rights Reserved. A West Australian methicillin-resistant Staphylococcus aureus strain (WA MRSA-59) was characterized by microarray and sequencing. Its pseudo-staphylococcal cassette chromosome mec (SCCmec) element comprised dcs, Q9XB68-dcs, mvaS-SCC, Q5HJW6, dru, ugpQ, ydeM, mecA-mecR-mecI, txbi mecI, tnp IS431, copA2-mco (copper resistance), ydhK, arsC-arsB-arsR (arsenic resistance), open reading frame PT43, and per-2. Recombinase genes, xylR (mecR2), and PSM-mec (phenol-soluble modulin) were absent. We suggest that mec complex A should be split into two subtypes. One harbors PSM-mec and xylR (mecR2). It is found in SCCmec types II, III, and VIII. The second subtype, described herein, is present in WA MRSA-59 and some coagulasenegative staphylococci.

dc.titleA Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element
dc.typeJournal Article
dcterms.source.volume59
dcterms.source.number11
dcterms.source.startPage7142
dcterms.source.endPage7144
dcterms.source.issn0066-4804
dcterms.source.titleAntimicrobial Agents and Chemotherapy
curtin.departmentSchool of Biomedical Sciences
curtin.accessStatusOpen access via publisher


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