A one-pot, three-component, microwave-assisted synthesis of novel 7-amino-substituted 4-aminopyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles
| dc.contributor.author | Lim, F. | |
| dc.contributor.author | Luna, Giuseppe | |
| dc.contributor.author | Dolzhenko, Anton | |
| dc.date.accessioned | 2017-01-30T15:15:37Z | |
| dc.date.available | 2017-01-30T15:15:37Z | |
| dc.date.created | 2015-12-10T04:26:13Z | |
| dc.date.issued | 2015 | |
| dc.identifier.citation | Lim, F. and Luna, G. and Dolzhenko, A. 2015. A one-pot, three-component, microwave-assisted synthesis of novel 7-amino-substituted 4-aminopyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles. Tetrahedron Letters. 56: pp. 7016-7019. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/44655 | |
| dc.identifier.doi | 10.1016/j.tetlet.2015.11.006 | |
| dc.description.abstract |
The synthesis of novel 7-amino-substituted pyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles was achieved via a three-component reaction of 3-amino-substituted 5-aminopyrazole-4-carbonitriles, cyanamide and triethyl orthoformate under microwave irradiation. Under catalyst-free conditions, this three-component reaction accommodated a generous diversity of amino substituents making it ideal for the generation of compound libraries for drug discovery processes. | |
| dc.title | A one-pot, three-component, microwave-assisted synthesis of novel 7-amino-substituted 4-aminopyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles | |
| dc.type | Journal Article | |
| dcterms.source.volume | 56 | |
| dcterms.source.startPage | 7016 | |
| dcterms.source.endPage | 7019 | |
| dcterms.source.issn | 0040-4039 | |
| dcterms.source.title | Tetrahedron Letters | |
| curtin.department | School of Pharmacy | |
| curtin.accessStatus | Fulltext not available |
Files in this item
| Files | Size | Format | View |
|---|---|---|---|
|
There are no files associated with this item. |
|||