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    Hemodynamic effect of calcifed plaque on blood flow in carotid artery disease: A preliminary study - Hemodynamic effect of calcified plaque

    Access Status
    Fulltext not available
    Authors
    Sun, Zhonghua
    Mwipatayi, B.
    Chaichana, T.
    Ng, Curtise Kin Cheung
    Date
    2009
    Type
    Conference Paper
    
    Metadata
    Show full item record
    Citation
    Sun, Z. and Mwipatayi, B. and Chaichana, T. and Ng, C.K.C. 2009. Hemodynamic effect of calcifed plaque on blood flow in carotid artery disease: A preliminary study - Hemodynamic effect of calcified plaque.
    Source Title
    3rd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2009
    DOI
    10.1109/ICBBE.2009.5162900
    ISBN
    9781424429028
    School
    Department of Medical Radiation Sciences
    URI
    http://hdl.handle.net/20.500.11937/4615
    Collection
    • Curtin Research Publications
    Abstract

    The purpose of the study is to investigate the hemodynamic effect of calcified carotid plaque on blood flow in patients diagnosed with carotid artery disease. Two carotid artery models were generated based on a sample patient data, with normal and calcified carotid artery appearances. Circular calcified carotid plaque was found at the carotid bifurcation based on 3D computed tomography images. A computational fluid dynamics was performed to analyze the changes of blood flow in different situations. Our results showed that apparent turbulence was found in the diastolic phase at the carotid bifurcation in normal carotid artery geometry. In the presence of the calcified plaque, the flow velocity was increased to some extent, indicating the effect of plaque on hemodynamic changes. Wall shear stress was noticed to decrease at the aortic branches, and this indicates the potential risk of developing stenosis at this area. Our preliminary study demonstrates fluid structure interaction between calcified plaque and artery in terms of flow changes and wall shear stress. ©2009 IEEE.

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