Show simple item record

dc.contributor.authorLiu, C.
dc.contributor.authorGong, Z.
dc.contributor.authorTeo, Kok Lay
dc.contributor.authorLoxton, Ryan
dc.contributor.authorFeng, E.
dc.identifier.citationLiu, C. and Gong, Z. and Teo, K.L. and Loxton, R. and Feng, E. 2016. Bi-objective dynamic optimization of a nonlinear time-delay system in microbial batch process. Optimization Letters. 12 (6): pp. 1249-1264.

In this paper, we propose a bi-objective dynamic optimization model involving a nonlinear time-delay system to optimize the 1,3-propanediol (1,3-PD) production in a microbial batch process, where the productivity of 1,3-PD and the consumption rate of glycerol are taken as the two objectives. The initial concentrations of biomass and glycerol, and the terminal time of the process are the decision variables. By a time-scaling transformation, we first transform the problem to the one with fixed terminal time but involving a new system with variable time-delay. The normalized normal constraint method is then used to convert the resulting problem into a sequence of single-objective dynamic optimization problems. A gradient-based optimization method incorporating the constraint transcription technique is developed to solve each of these single-objective dynamic optimization problems. Finally, numerical results are provided to demonstrate the effectiveness of the proposed solution method.

dc.publisherSpringer Verlag
dc.titleBi-objective dynamic optimization of a nonlinear time-delay system in microbial batch process
dc.typeJournal Article
dcterms.source.titleOptimization Letters
curtin.departmentDepartment of Mathematics and Statistics
curtin.accessStatusOpen access

Files in this item


This item appears in the following Collection(s)

Show simple item record