Show simple item record

dc.contributor.authorLawlor, K.
dc.contributor.authorKaur, Pritinder
dc.date.accessioned2018-12-13T09:08:43Z
dc.date.available2018-12-13T09:08:43Z
dc.date.created2018-12-12T02:47:11Z
dc.date.issued2015
dc.identifier.citationLawlor, K. and Kaur, P. 2015. Dermal contributions to human interfollicular epidermal architecture and self-renewal. International Journal of Molecular Science. 16 (12): pp. 28098-28107.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/71077
dc.identifier.doi10.3390/ijms161226078
dc.description.abstract

© 2015 by the authors; licensee MDPI, Basel, Switzerland. The human interfollicular epidermis is renewed throughout life by populations of proliferating basal keratinocytes. Though interfollicular keratinocyte stem cells have been identified, it is not known how self-renewal in this compartment is spatially organized. At the epidermal-dermal junction, keratinocytes sit atop a heterogeneous mix of dermal cells that may regulate keratinocyte self-renewal by influencing local tissue architecture and signalling microenvironments. Focusing on the rete ridges and complementary dermal papillae in human skin, we review the identity and organisation of abundant dermal cells types and present evidence for interactions between the dermal microenvironment and the interfollicular keratinocytes.

dc.publisherMDPI AG
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleDermal contributions to human interfollicular epidermal architecture and self-renewal
dc.typeJournal Article
dcterms.source.volume16
dcterms.source.number12
dcterms.source.startPage28098
dcterms.source.endPage28107
dcterms.source.issn1661-6596
dcterms.source.titleInternational Journal of Molecular Science
curtin.departmentSchool of Pharmacy and Biomedical Sciences
curtin.accessStatusOpen access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

https://creativecommons.org/licenses/by/4.0/
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/