Electrospun Silk Nanofibre Mats and Their Potential as Tissue Scaffolds
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In this study new electrospun silk fibroin (SF) based scaffolds were developed and their material and biocompatibility characteristics evaluated. Three types of SF based scaffolds were generated: SF/halloysite (HNT), SF/gelatin and SF/collagen. Scaffolds chosen for their material and biocompatibility characteristics were coated with fibroblast extracellular matrix and their efficacy for supporting primary human keratinocyte expansion were investigated. Collectively these data indicated SF/HNT scaffolds have merit for wound healing and tissue engineering applications.
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