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dc.contributor.authorSun, Zhonghua
dc.contributor.authorNg, Curtise
dc.contributor.authorBibombe, P.
dc.contributor.authorChaichana, T.
dc.contributor.editorThe 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009
dc.date.accessioned2017-01-30T11:55:39Z
dc.date.available2017-01-30T11:55:39Z
dc.date.created2010-02-09T20:02:03Z
dc.date.issued2009
dc.identifier.citationSun, Zhonghua and Ng, Curtise and Bibombe, Patrice and Chaichana, Thanapong. 2009. Hemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study, in The 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009 (ed), The 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009, Jun 11 2009. Beijing.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/16419
dc.description.abstract

The purpose of the study is to investigate the hemodynamic effect of calcified carotid plaque on blood flow in patients diagnosed with carotid artery disease. Two carotid artery models were generated based on a patient data, with normal and calcified carotid artery appearances. Circular calcified carotid plaque was found at the carotid bifurcation based on 3D computed tomography images. A computational fluid dynamics was performed to analyze the changes of blood flow in different situations. Our results showed that apparent turbulence was found in the diastolic phase at the carotid bifurcation in normal carotid artery geometry. In the presence of the calcified plaque, the flow velocity was increased to some extent, indicating the effect of plaque on hemodynamic changes. Wall shear stress was noticed to be maximal at the aortic bifurcation, and this indicates the potential risk of developing stenosis at this area. Our preliminary study demonstrates fluid structure interaction between calcified plaque and artery in terms of flow changes and wall shear stress.

dc.publisherThe 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009
dc.subjectModel
dc.subjectCalcification
dc.subjectBlood flow
dc.subjectComputed tomography
dc.subjectCarotid artery disease
dc.titleHemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study
dc.typeConference Paper
dcterms.source.titleThe 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009
dcterms.source.seriesThe 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009
dcterms.source.conferenceThe 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009
dcterms.source.conference-start-dateJun 11 2009
dcterms.source.conferencelocationBeijing
dcterms.source.placeBeijing
curtin.note

Copyright © 2009 IEEE This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.

curtin.accessStatusOpen access
curtin.facultySchool of Science and Computing
curtin.facultyFaculty of Science and Engineering
curtin.facultyDepartment of Imaging and Applied Physics


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