The Emerging Role of PEDF in Stem Cell Biology
dc.contributor.author | Elahy, Mina | |
dc.contributor.author | Baindur-Hudson, Swati | |
dc.contributor.author | Dass, Crispin | |
dc.date.accessioned | 2017-01-30T13:32:33Z | |
dc.date.available | 2017-01-30T13:32:33Z | |
dc.date.created | 2013-03-26T20:00:49Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | Elahy, Mina and Baindur-Hudson, Swati and Dass, Crispin R. 2012. The Emerging Role of PEDF in Stem Cell Biology. Journal of Biomedicine and Biotechnology. 2012: Article ID 239091. | |
dc.identifier.uri | http://hdl.handle.net/20.500.11937/32715 | |
dc.identifier.doi | 10.1155/2012/239091 | |
dc.description.abstract |
Encoded by a single gene, PEDF is a 50 kDa glycoprotein that is highly conserved and is widely expressed among many tissues. Most secreted PEDF deposits within the extracellular matrix, with cell-type-specific functions. While traditionally PEDF is known as a strong antiangiogenic factor, more recently, as this paper highlights, PEDF has been linked with stem cell biology, and there is now accumulating evidence demonstrating the effects of PEDF in a variety of stem cells, mainly in supporting stem cell survival and maintaining multipotency. | |
dc.publisher | Hindawi Publishing Corporation | |
dc.title | The Emerging Role of PEDF in Stem Cell Biology | |
dc.type | Journal Article | |
dcterms.source.volume | 2012 | |
dcterms.source.startPage | 1 | |
dcterms.source.endPage | 6 | |
dcterms.source.issn | 2314-6133 | |
dcterms.source.title | Journal of Biomedicine and Biotechnology | |
curtin.note |
This open access article is distributed under the Creative Commons license | |
curtin.department | ||
curtin.accessStatus | Open access |