Show simple item record

dc.contributor.authorDonato, C.
dc.contributor.authorCannan, D.
dc.contributor.authorBogdanovic-Sakran, N.
dc.contributor.authorSnelling, Thomas
dc.contributor.authorKirkwood, C.
dc.date.accessioned2017-08-24T02:17:56Z
dc.date.available2017-08-24T02:17:56Z
dc.date.created2017-08-23T07:21:45Z
dc.date.issued2012
dc.identifier.citationDonato, C. and Cannan, D. and Bogdanovic-Sakran, N. and Snelling, T. and Kirkwood, C. 2012. Characterisation of a G9P[8] rotavirus strain identified during a gastroenteritis outbreak in Alice Springs, Australia post Rotarix™ vaccine introduction. Vaccine. 30 (SUPPL. 1).
dc.identifier.urihttp://hdl.handle.net/20.500.11937/55296
dc.identifier.doi10.1016/j.vaccine.2011.07.119
dc.description.abstract

A large rotavirus gastroenteritis outbreak occurred in the Alice Springs region of the Northern Territory, Australia from the 12th of March until the 11th of July 2007. The outbreak occurred five months after the introduction of the Rotarix™ vaccine. Electropherotype and sequence analysis demonstrated that a single G9P[8] strain was responsible for the outbreak and that the strain remained highly conserved during the outbreak period. The outbreak strain contained amino acid changes in regions of the VP7 and NSP4 genes, with known biological function, when compared to previously characterised G9P[8] strains from Australia and other international locations. The recent vaccine introduction was unlikely to have influenced genotype selection in this setting. Importantly, Rotarix™ vaccine was highly effective against the G9P[8] outbreak strain. © 2011 Elsevier Ltd.

dc.publisherElsevier
dc.titleCharacterisation of a G9P[8] rotavirus strain identified during a gastroenteritis outbreak in Alice Springs, Australia post Rotarix™ vaccine introduction
dc.typeJournal Article
dcterms.source.volume30
dcterms.source.numberSUPPL. 1
dcterms.source.issn0264-410X
dcterms.source.titleVaccine
curtin.departmentSchool of Public Health
curtin.accessStatusFulltext not available


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record