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dc.contributor.authorLandwehr, K.R.
dc.contributor.authorHillas, J.
dc.contributor.authorMead-Hunter, Ryan
dc.contributor.authorO'Leary, R.A.
dc.contributor.authorKicic, Anthony
dc.contributor.authorMullins, Ben
dc.contributor.authorLarcombe, Alexander
dc.date.accessioned2019-10-31T04:27:40Z
dc.date.available2019-10-31T04:27:40Z
dc.date.issued2019
dc.identifier.citationLandwehr, K.R. and Hillas, J. and Mead-Hunter, R. and O'Leary, R.A. and Kicic, A. and Mullins, B.J. and Larcombe, A.N. 2019. Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells. Environmental Science and Technology. 53 (19): pp. 11437-11446.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/76699
dc.identifier.doi10.1021/acs.est.9b01671
dc.description.abstract

© 2019 American Chemical Society. As global biodiesel production increases, there are concerns over the potential health impact of exposure to the exhaust, particularly in regard to young children who are at high risk because of their continuing lung development. Using human airway epithelial cells obtained from young children, we compared the effects of exposure to exhaust generated by a diesel engine with Euro V/VI emission controls running on conventional diesel (ultra-low-sulfur mineral diesel, ULSD), soy biodiesel (B100), or a 20% blend of soy biodiesel with diesel (B20). The exhaust output of biodiesel was found to contain significantly more respiratory irritants, including NOx, CO, and CO2, and a larger overall particle mass. Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust. These results have concerning implications for potential global health impacts, particularly for the pediatric population.

dc.languageEnglish
dc.publisherAMER CHEMICAL SOC
dc.relation.sponsoredbyhttp://purl.org/au-research/grants/arc/DP170104346
dc.subjectScience & Technology
dc.subjectTechnology
dc.subjectLife Sciences & Biomedicine
dc.subjectEngineering, Environmental
dc.subjectEnvironmental Sciences
dc.subjectEngineering
dc.subjectEnvironmental Sciences & Ecology
dc.subjectCARBON-MONOXIDE
dc.subjectNITROGEN-DIOXIDE
dc.subject2ND-GENERATION BIODIESEL
dc.subjectRESPIRATORY HEALTH
dc.subjectEMISSIONS
dc.subjectEXPOSURE
dc.subjectPOLLUTION
dc.subjectPARTICLES
dc.subjectENGINE
dc.subjectINHALATION
dc.titleSoy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells
dc.typeJournal Article
dcterms.source.volume53
dcterms.source.number19
dcterms.source.startPage11437
dcterms.source.endPage11446
dcterms.source.issn0013-936X
dcterms.source.titleEnvironmental Science and Technology
dc.date.updated2019-10-31T04:27:40Z
curtin.note

This document is the Accepted Manuscript version of a Published Work that appeared in final form in Environmental Science and Technology, copyright © American Chemical Society, after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.est.9b01671.

curtin.departmentSchool of Public Health
curtin.accessStatusOpen access
curtin.facultyFaculty of Health Sciences
curtin.contributor.orcidMead-Hunter, Ryan [0000-0003-2025-4449]
curtin.contributor.orcidKicic, Anthony [0000-0002-0008-9733]
curtin.contributor.orcidMullins, Ben [0000-0002-6722-1073]
curtin.contributor.orcidLarcombe, Alexander [0000-0003-4196-4482]
curtin.contributor.researcheridLarcombe, Alexander [A-7704-2011]
dcterms.source.eissn1520-5851
curtin.contributor.scopusauthoridMead-Hunter, Ryan [36705125800]
curtin.contributor.scopusauthoridKicic, Anthony [6507472922]
curtin.contributor.scopusauthoridMullins, Ben [7003349055]
curtin.contributor.scopusauthoridLarcombe, Alexander [6508025368]


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